Gene Expression: HLA-B

Gene Data

  • Gene Symbol: HLA-B
  • Gene ID: 3106
  • Synonyms: AS, HLAB, SPDA1
  • Description: major histocompatibility complex, class I, B
  • Database Refs: HGNC:4932, MIM:142830, Ensembl:ENSG00000234745, HPRD:00828, Vega:OTTHUMG00000031153
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 5 out of 69 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 542 diseases, scroll to view all:
  1. Acquired immunodeficiency syndrome
  2. Acute leukemia
  3. Acute myeloid leukemia
  4. Acute retinal necrosis syndrome
  5. Adenocarcinoma
  6. Adrenal gland disease
  7. Adrenal gland disease
  8. Adrenal gland disease
  9. Adrenal hyperplasia
  10. Adrenal hyperplasia
  11. Adrenal hyperplasia
  12. Alkaptonuria
  13. Alopecia areata
  14. Amyloidosis
  15. Anemia
  16. Ankylosing spondylitis
  17. Ankylosing spondylitis
  18. Ankylosing spondylitis
  19. Ankylosing spondylitis
  20. Ankylosis
  21. Anterior uveitis
  22. Anterior uveitis
  23. Anterior uveitis
  24. Anterior uveitis
  25. Aortic incompetence
  26. Aortic valve disease
  27. Aortic valve insufficiency
  28. Aortitis
  29. Aphthous stomatitis
  30. Aplastic anemia
  31. Arthritis
  32. Arthritis
  33. Arthritis
  34. Arthritis
  35. Arthropathy
  36. Arthropathy
  37. Autoimmune disease of cardiovascular sys
  38. Autoimmune disease of cardiovascular sys
  39. Autoimmune disease of cardiovascular sys
  40. Autoimmune disease of cardiovascular sys
  41. Autoimmune disease of endocrine system
  42. Autoimmune disease of gastrointestinal t
  43. Autoimmune disease of the nervous system
  44. Autoimmune disease of urogenital tract
  45. Autoimmune disease of urogenital tract
  46. Autoimmune thyroiditis
  47. Axial osteomalacia
  48. B cell deficiency
  49. B-cell lymphocytic neoplasm
  50. B-cell lymphocytic neoplasm
  51. Bacterial infectious disease
  52. Bacterial infectious disease
  53. Bacterial infectious disease
  54. Balanitis
  55. Band keratopathy
  56. Behcet's disease
  57. Behcet's disease
  58. Behcet's disease
  59. Behcet's disease
  60. Bone disease
  61. Bone disease
  62. Bone disease
  63. Bone disease
  64. Bone inflammation disease
  65. Bone inflammation disease
  66. Bone inflammation disease
  67. Bone inflammation disease
  68. Bone marrow cancer
  69. Bone marrow disease
  70. Bone marrow disease
  71. Bone remodeling disease
  72. Borna disease
  73. Brain disease
  74. Brain neoplasm
  75. Breast cancer
  76. Bronchiolitis obliterans
  77. Bronchiolitis obliterans
  78. Burkitt's lymphoma
  79. Burkitt's lymphoma
  80. Bursitis
  81. Cancer
  82. Cancer
  83. Cancer
  84. Caplan's syndrome
  85. Carbohydrate metabolism disease
  86. Carbohydrate metabolism disease
  87. Carbohydrate metabolism disease
  88. Carcinoma
  89. Carcinoma
  90. Cardiovascular cancer
  91. Cardiovascular system disease
  92. Cardiovascular system disease
  93. Cardiovascular system disease
  94. Cardiovascular system disease
  95. Celiac disease
  96. Cell type cancer
  97. Cell type cancer
  98. Central nervous system disease
  99. Central nervous system disease
  100. Central nervous system neoplasm
  101. Cervicitis
  102. Cervix disease
  103. Chorioretinitis
  104. Chronic myeloid leukemia
  105. Coccidiosis
  106. Colon cancer
  107. Colon carcinoma
  108. Colorectal cancer
  109. Congenital adrenal hyperplasia
  110. Congenital adrenal hyperplasia
  111. Congenital adrenal hyperplasia
  112. Conjunctival disease
  113. Conjunctivitis
  114. Connective tissue disease
  115. Connective tissue disease
  116. Connective tissue disease
  117. Connective tissue neoplasm
  118. Crohn's disease
  119. Cutaneous mastocytosis
  120. Cystoid macular edema
  121. Demyelinating disease
  122. Demyelinating disease
  123. Dermatitis
  124. Dermatitis
  125. Dermatomyositis
  126. Diabetes mellitus
  127. Diabetes mellitus
  128. Diabetes mellitus
  129. Diabetes mellitus
  130. Diabetes mellitus type 1
  131. Diabetes mellitus type 1
  132. Diabetes mellitus type 1
  133. Diarrhea
  134. Diffuse idiopathic skeletal hyperostosis
  135. Disease
  136. Disease
  137. Disease
  138. Disease
  139. Disease by infectious agent
  140. Disease by infectious agent
  141. Disease by infectious agent
  142. Disease by infectious agent
  143. Disease of anatomical entity
  144. Disease of anatomical entity
  145. Disease of anatomical entity
  146. Disease of anatomical entity
  147. Disease of cellular proliferation
  148. Disease of cellular proliferation
  149. Disease of cellular proliferation
  150. Disease of metabolism
  151. Disease of metabolism
  152. Disease of metabolism
  153. Disease of metabolism
  154. Dysentery
  155. Encephalitis
  156. Encephalomyelitis
  157. Endocrine pancreas disease
  158. Endocrine pancreas disease
  159. Endocrine pancreas disease
  160. Endocrine system disease
  161. Endocrine system disease
  162. Endocrine system disease
  163. Endocrine system disease
  164. Endophthalmitis
  165. Enthesopathy
  166. Epididymitis
  167. Epididymitis
  168. Eye and adnexa disease
  169. Eye and adnexa disease
  170. Eye and adnexa disease
  171. Eye disease
  172. Eye disease
  173. Eye disease
  174. Fasciitis
  175. Female reproductive system disease
  176. Female reproductve organ cancer
  177. Fibrosarcoma
  178. Fibrous tissue neoplasm
  179. Frozen shoulder
  180. Fuchs' heterochromic uveitis
  181. Gastroenteritis
  182. Gastrointestinal system cancer
  183. Gastrointestinal system disease
  184. Gastrointestinal system disease
  185. Gastrointestinal system disease
  186. Gastrointestinal system disease
  187. Genitourinary cancer
  188. Genitourinary cancer
  189. Germ cell cancer
  190. Germ cell cancer
  191. Glioma
  192. Globe disease
  193. Globe disease
  194. Globe disease
  195. Glomerulonephritis
  196. Glomerulonephritis
  197. Glucose metabolism disease
  198. Glucose metabolism disease
  199. Glucose metabolism disease
  200. Goiter
  201. Granuloma inguinale
  202. Graves' disease
  203. Habitual abortion
  204. Habitual abortion
  205. Heart valve disease
  206. Hematologic cancer
  207. Hematologic cancer
  208. Hematopoietic system disease
  209. Hematopoietic system disease
  210. Hemochromatosis
  211. Hemochromatosis
  212. Hepatitis
  213. Hepatitis
  214. Hepatitis
  215. Hepatitis B
  216. Hepatitis B
  217. Hepatobiliary disease
  218. Hepatobiliary disease
  219. Hepatobiliary disease
  220. Hepatocellular carcinoma
  221. Hidradenitis
  222. Hidradenitis suppurativa
  223. Human immunodeficiency virus infectious
  224. Human immunodeficiency virus infectious
  225. Human immunodeficiency virus infectious
  226. Human immunodeficiency virus infectious
  227. Hyperostosis
  228. Hypersensitivity reaction disease
  229. Hypersensitivity reaction disease
  230. Hypersensitivity reaction disease
  231. Hypersensitivity reaction disease
  232. Hypersensitivity reaction type II diseas
  233. Hypersensitivity reaction type II diseas
  234. Hypersensitivity reaction type II diseas
  235. Hypersensitivity reaction type II diseas
  236. Hypersensitivity reaction type IV diseas
  237. Hypersensitivity reaction type IV diseas
  238. Hypersensitivity reaction type IV diseas
  239. Hypertension
  240. Hyperthyroidism
  241. Hypertrophic cardiomyopathy
  242. Hypopyon
  243. IgA glomerulonephritis
  244. Immune system cancer
  245. Immune system disease
  246. Immune system disease
  247. Immune system disease
  248. Immune system disease
  249. Immunoglobulin alpha deficiency
  250. Immunoglobulin alpha deficiency
  251. Inborn errors metal metabolism
  252. Inborn errors metal metabolism
  253. Inborn errors of metabolism
  254. Inborn errors steroid metabolism
  255. Inborn errors steroid metabolism
  256. Inborn errors steroid metabolism
  257. Inclusion body myositis
  258. Infectious mononucleosis
  259. Inflammatory bowel disease
  260. Inflammatory bowel disease
  261. Inflammatory bowel disease
  262. Influenza
  263. Influenza
  264. Integumentary system disease
  265. Integumentary system disease
  266. Integumentary system disease
  267. Integumentary system disease
  268. Intermediate uveitis
  269. Intermediate uveitis
  270. Interstitial lung disease
  271. Intestinal cancer
  272. Intestinal disease
  273. Intestinal disease
  274. Intestinal disease
  275. Intestinal infectious disease
  276. Intracranial neoplasm
  277. Intrinsic cardiomyopathy
  278. Iridocyclitis
  279. Iris disease
  280. Iritis
  281. Ischemia
  282. Juvenile rheumatoid arthritis
  283. Juvenile rheumatoid arthritis
  284. Kaposi's sarcoma
  285. Kaposi's sarcoma
  286. Kidney cancer
  287. Kidney cancer
  288. Kidney disease
  289. Kidney disease
  290. Kidney failure
  291. Large intestine cancer
  292. Leprosy
  293. Leukemia
  294. Leukemia
  295. Leukocyte disease
  296. Listeriosis
  297. Liver cancer
  298. Liver carcinoma
  299. Liver cirrhosis
  300. Liver disease
  301. Liver disease
  302. Liver disease
  303. Lower respiratory tract disease
  304. Lower respiratory tract disease
  305. Lung cancer
  306. Lung carcinoma
  307. Lung disease
  308. Lung disease
  309. Lupus erythematosus
  310. Lupus erythematosus
  311. Lupus erythematosus
  312. Lymphoblastic leukemia
  313. Lymphoblastic leukemia
  314. Lymphoid leukemia
  315. Lymphoid leukemia
  316. Lymphoma
  317. Lymphoma
  318. Lymphoproliferative disease
  319. Lymphoproliferative disease
  320. Lymphoproliferative disease
  321. Macular retinal edema
  322. Malaria
  323. Male reproductive system disease
  324. Malignant vascular tumor
  325. Mast cell neoplasm
  326. Mastocytosis
  327. Mature B-cell lymphocytic neoplasm
  328. Mature B-cell lymphocytic neoplasm
  329. Measles
  330. Melanoma
  331. Melanoma
  332. Melanoma
  333. Membranous glomerulonephritis
  334. Mesenchymal cell neoplasm
  335. Mineral metabolism disease
  336. Mineral metabolism disease
  337. Multiple sclerosis
  338. Multiple sclerosis
  339. Mumps
  340. Muscle tissue disease
  341. Muscle tissue disease
  342. Muscle tissue disease
  343. Muscular disease
  344. Muscular disease
  345. Muscular disease
  346. Musculoskeletal system disease
  347. Musculoskeletal system disease
  348. Musculoskeletal system disease
  349. Musculoskeletal system disease
  350. Myasthenia gravis
  351. Myeloid leukemia
  352. Myeloma
  353. Myocarditis
  354. Myopathy
  355. Myopathy
  356. Myopathy
  357. Myositis
  358. Myositis
  359. Nail disease
  360. Nasopharynx cancer
  361. Nasopharynx carcinoma
  362. Neoplasm of autonomic nervous system
  363. Nephritis
  364. Nephritis
  365. Nervous system cancer
  366. Nervous system disease
  367. Nervous system disease
  368. Nervous system disease
  369. Neuroblastoma
  370. Neurodegenerative disease
  371. Neurodegenerative disease
  372. Neuromuscular disease
  373. Neuromuscular junction disease
  374. Neuromuscular junction disease
  375. Neuropathy
  376. Olecranon bursitis
  377. Optic neuritis
  378. Optic papillitis
  379. Organ system cancer
  380. Organ system cancer
  381. Organ system cancer
  382. Osteoarthritis
  383. Osteomyelitis
  384. Otosclerosis
  385. Ovarian cancer
  386. Palindromic rheumatism
  387. Pancreas disease
  388. Pancreas disease
  389. Pancreas disease
  390. Panuveitis
  391. Panuveitis
  392. Panuveitis
  393. Parasitic infectious disease
  394. Parasitic infectious disease
  395. Parasitic infectious disease
  396. Parasitic protozoa infectious disease
  397. Parasitic protozoa infectious disease
  398. Parasitic protozoa infectious disease
  399. Pars planitis
  400. Pars planitis
  401. Penile disease
  402. Periostitis
  403. Peripheral nervous system neoplasm
  404. Phlebitis
  405. Plantar fasciitis
  406. Posterior scleritis
  407. Posterior uveitis
  408. Posterior uveitis
  409. Posterior uveitis
  410. Pregnancy complication
  411. Pregnancy complication
  412. Pregnancy disease
  413. Pregnancy disease
  414. Primary bacterial infectious disease
  415. Primary bacterial infectious disease
  416. Primary bacterial infectious disease
  417. Primary biliary cirrhosis
  418. Primary biliary cirrhosis
  419. Primary immunodeficiency disease
  420. Primary immunodeficiency disease
  421. Psoriasis
  422. Psoriasis
  423. Psoriasis
  424. Psoriasis
  425. Psoriatic arthritis
  426. Psoriatic arthritis
  427. Psoriatic arthritis
  428. Psoriatic arthritis
  429. Pulmonary tuberculosis
  430. Pustulosis of palm and sole
  431. Reactive arthritis
  432. Reactive arthritis
  433. Renal carcinoma
  434. Renal cell carcinoma
  435. Reproductive organ cancer
  436. Reproductive system disease
  437. Reproductive system disease
  438. Respiratory system cancer
  439. Respiratory system cancer
  440. Respiratory system disease
  441. Respiratory system disease
  442. Retinal edema
  443. Retinal vasculitis
  444. Retinal vasculitis
  445. Retinitis
  446. Rheumatic disease
  447. Rheumatic fever
  448. Rheumatic fever
  449. Rheumatic heart disease
  450. Rheumatoid arthritis
  451. Rheumatoid arthritis
  452. Rheumatoid arthritis
  453. SAPHO syndrome
  454. Sarcoidosis
  455. Sarcoidosis
  456. Sarcoma
  457. Scleral disease
  458. Scleritis
  459. Sensory system disease
  460. Sensory system disease
  461. Sensory system disease
  462. Septic arthritis
  463. Shigellosis
  464. Skin cancer
  465. Skin disease
  466. Skin disease
  467. Skin disease
  468. Skin disease
  469. Soft tissue cancer
  470. Specific bursitis often of occupational
  471. Spondylitis
  472. Spondyloarthropathy
  473. Spontaneous abortion
  474. Spontaneous abortion
  475. Squamous cell carcinoma
  476. Stevens-Johnson syndrome
  477. Stevens-Johnson syndrome
  478. Stevens-Johnson syndrome
  479. Stevens-Johnson syndrome
  480. Stomatitis
  481. Syndrome
  482. Syndrome
  483. Syndrome
  484. Syndrome
  485. Synovitis
  486. Systemic lupus erythematosus
  487. Systemic lupus erythematosus
  488. Systemic lupus erythematosus
  489. Takayasu's arteritis
  490. Takayasu's arteritis
  491. Takayasu's arteritis
  492. Takayasu's arteritis
  493. Tendinitis
  494. Tenosynovitis
  495. Tetanus
  496. Thoracic cancer
  497. Thrombophlebitis
  498. Thymoma
  499. Thymus cancer
  500. Thyroid gland disease
  501. Thyroiditis
  502. Thyrotoxicosis
  503. Toxocariasis
  504. Toxoplasmosis
  505. Transient arthritis
  506. Tuberculosis
  507. Tuberculosis
  508. Typhoid fever
  509. Ulcerative colitis
  510. Ulcerative colitis
  511. Urethral disease
  512. Urethritis
  513. Urinary system disease
  514. Urinary system disease
  515. Urinary system disease
  516. Urinary tract cancer
  517. Urinary tract cancer
  518. Uveal disease
  519. Uveal disease
  520. Uveal disease
  521. Uveal disease
  522. Uveitis
  523. Uveitis
  524. Uveitis
  525. Uveitis
  526. Vaccinia
  527. Vascular disease
  528. Vascular disease
  529. Vascular disease
  530. Vasculitis
  531. Vasculitis
  532. Vasculitis
  533. Vasculitis
  534. Viral infectious disease
  535. Viral infectious disease
  536. Viral infectious disease
  537. Viral infectious disease
  538. Vogt-Koyanagi-Harada disease
  539. Vogt-Koyanagi-Harada disease
  540. Vulvar disease
  541. Vulvitis
  542. Whipple disease

Stage Associations

This gene is associated with the following stages: