Gene Expression: POLG

Gene Data

  • Gene Symbol: POLG
  • Gene ID: 5428
  • Synonyms: MDP1, MIRAS, MTDPS4A, MTDPS4B, PEO, POLG1, POLGA, SANDO, SCAE
  • Description: polymerase (DNA directed), gamma
  • Database Refs: HGNC:9179, MIM:174763, Ensembl:ENSG00000140521, HPRD:01438, Vega:OTTHUMG00000149646
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 2 out of 24 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 54 diseases, scroll to view all:
  1. Alpers syndrome
  2. Axonal neuropathy
  3. Barth syndrome
  4. Brain disease
  5. Central nervous system disease
  6. Cerebral degeneration
  7. Chronic progressive external ophthalmopl
  8. Cortical blindness
  9. Cranial nerve disease
  10. Disease
  11. Disease of anatomical entity
  12. Disease of metabolism
  13. Epilepsia partialis continua
  14. Epilepsy
  15. Generalized convulsive epilepsy
  16. Generalized epilepsy
  17. Grand mal status epilepticus
  18. Inborn errors of metabolism
  19. Infantile onset spinocerebellar ataxia
  20. Infertility
  21. Intestinal pseudo-obstruction
  22. Intractable epilepsy
  23. Lactic acidosis
  24. Leigh disease
  25. Lipodystrophy
  26. Male infertility
  27. Male reproductive system disease
  28. MELAS syndrome
  29. Migraine
  30. Mitochondrial disease
  31. Mitochondrial encephalomyopathy
  32. Mitochondrial myopathy
  33. Multiple symmetric lipomatosis
  34. Muscle tissue disease
  35. Muscular disease
  36. Musculoskeletal system disease
  37. Myopathy
  38. Nervous system disease
  39. Neurodegenerative disease
  40. Neuromuscular disease
  41. Neuropathy
  42. Ocular motility disease
  43. Ophthalmoplegia
  44. Pearson syndrome
  45. Peripheral nervous system disease
  46. Peripheral neuropathy
  47. Reproductive system disease
  48. Sensory peripheral neuropathy
  49. Spinocerebellar ataxia
  50. Spinocerebellar degeneration
  51. Status epilepticus
  52. tonic-clonic epilepsy
  53. Visual cortex disease
  54. Visual pathway disease

Stage Associations

This gene is associated with the following stages: