History:GENE:PKD1    GENE:CRTC2    GENE:CCR9    GENE:IL10RA    GENE:TREX1    

Gene Expression: PLP1

Gene Data

  • Gene Symbol: PLP1
  • Gene ID: 5354
  • Synonyms: GPM6C, HLD1, MMPL, PLP, PLP/DM20, PMD, SPG2
  • Description: proteolipid protein 1
  • Database Refs: HGNC:9086, MIM:300401, Ensembl:ENSG00000123560, HPRD:02321, Vega:OTTHUMG00000022111
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 1 out of 14 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters: No Clusters were found

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 45 diseases, scroll to view all:
  1. Astigmatism
  2. Atrophic muscular disease
  3. Brain disease
  4. Central nervous system disease
  5. Cerebral degeneration
  6. Cerebral palsy
  7. Cerebrovascular accident
  8. Cerebrovascular disease
  9. Cocaine abuse
  10. Cognitive disease
  11. Corneal degeneration
  12. Corneal ectasia
  13. Demyelinating disease
  14. Disease
  15. Disease of anatomical entity
  16. Disease of mental health
  17. Encephalomyelitis
  18. Extratemporal epilepsy
  19. Hypersensitivity reaction disease
  20. Hypersensitivity reaction type II diseas
  21. Immune system disease
  22. Irregular astigmatism
  23. Keratoconus
  24. Leukodystrophy
  25. Melancholia
  26. Mental depression
  27. Mood disease
  28. Multiple sclerosis
  29. Muscle tissue disease
  30. Muscular disease
  31. Muscular dystrophy
  32. Myopathy
  33. Nervous system disease
  34. Neurodegenerative disease
  35. Neuromuscular disease
  36. Neuropathy
  37. Paraplegia
  38. Pelizaeus-Merzbacher disease
  39. Peripheral nervous system disease
  40. Peripheral neuropathy
  41. Psychogenic depressive psychosis
  42. Psychotic disease
  43. Spastic cerebral palsy
  44. Spastic paraplegia
  45. Spastic quadriplegia

Stage Associations

This gene is associated with the following stages: No Stages were found