Gene Expression: COMT

Gene Data

  • Gene Symbol: COMT
  • Gene ID: 1312
  • Synonyms: -
  • Description: catechol-O-methyltransferase
  • Database Refs: HGNC:2228, MIM:116790, Ensembl:ENSG00000093010, HPRD:00284, Vega:OTTHUMG00000150529
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 1 out of 11 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 68 diseases, scroll to view all:
  1. Agoraphobia
  2. Anxiety disease
  3. Attention deficit hyperactivity disease
  4. Autism
  5. Autism spectrum disease
  6. Basal ganglia disease
  7. Bipolar disease
  8. Borderline personality disease
  9. Brain disease
  10. Breast cancer
  11. Cancer
  12. Cannabis abuse
  13. Cannabis dependence
  14. Cardiovascular system disease
  15. Central nervous system disease
  16. Chromosomal disease
  17. Chronic schizophrenia
  18. Cognitive disease
  19. Conduct disease
  20. Developmental disease of mental health
  21. Diarrhea
  22. Disease
  23. Disease of anatomical entity
  24. Disease of cellular proliferation
  25. Disease of mental health
  26. Drug dependence
  27. Endogenous depression
  28. Endometrial cancer
  29. Female reproductve organ cancer
  30. Fibromyalgia
  31. Gastrointestinal system disease
  32. Genetic disease
  33. Genitourinary cancer
  34. Hallucinogen dependence
  35. Heroin dependence
  36. Hyperhomocysteinemia
  37. Hypertension
  38. Inborn errors of amino acid metabolism
  39. Kleptomania
  40. Mental depression
  41. Monogenic disease
  42. Mood disease
  43. Myositis
  44. Nervous system disease
  45. Neurodegenerative disease
  46. Opiate addiction
  47. Organ system cancer
  48. Parkinson's disease
  49. Personality disease
  50. Pervasive developmental disease
  51. Phobic disease
  52. Psychotic disease
  53. Reproductive organ cancer
  54. Schizoaffective disease
  55. Schizophrenia
  56. Secondary Parkinson disease
  57. Specific developmental disease
  58. Specific phobia
  59. Substance abuse
  60. Substance dependence
  61. substance-related disease
  62. Syndrome
  63. Thoracic cancer
  64. Uterine cancer
  65. Uterine fibroid
  66. Uterine neoplasm
  67. Vascular disease
  68. Velocardiofacial syndrome

Stage Associations

This gene is associated with the following stages: