History:GENE:HAX1    GENE:GJA4    GENE:DFNB31    

Gene Expression: AIRE

Gene Data

  • Gene Symbol: AIRE
  • Gene ID: 326
  • Synonyms: AIRE1, APECED, APS1, APSI, PGA1
  • Description: autoimmune regulator
  • Database Refs: HGNC:360, MIM:607358, Ensembl:ENSG00000160224, HPRD:06301, Vega:OTTHUMG00000086921
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 0 out of 19 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 67 diseases, scroll to view all:
  1. Addison's disease
  2. Adrenal cortex disease
  3. Adrenal cortical hypofunction
  4. Adrenal gland disease
  5. Alopecia
  6. Alopecia areata
  7. Alopecia universalis
  8. Autoimmune disease of endocrine system
  9. Autoimmune disease of gastrointestinal t
  10. Autoimmune disease of the nervous system
  11. Autoimmune hepatitis
  12. Autoimmune polyendocrine syndrome
  13. Autoimmune polyendocrine syndrome type 1
  14. Autoimmune thyroiditis
  15. Candidiasis
  16. Carbohydrate metabolism disease
  17. Cardiovascular system disease
  18. Chronic mucocutaneous candidiasis
  19. Corneal disease
  20. Dental enamel hypoplasia
  21. Diabetes mellitus
  22. Disease
  23. Disease by infectious agent
  24. Disease of anatomical entity
  25. Disease of metabolism
  26. Endocrine pancreas disease
  27. Endocrine system disease
  28. Extrinsic cardiomyopathy
  29. Eyelid disease
  30. Fungal infectious disease
  31. Gastrointestinal system disease
  32. Glucose metabolism disease
  33. Hair disease
  34. Heart disease
  35. Heart failure
  36. Hepatitis
  37. Hypersensitivity reaction disease
  38. Hypersensitivity reaction type II diseas
  39. Hypoparathyroidism
  40. Hypothyroidism
  41. Hypotrichosis
  42. Immune system cancer
  43. Immune system disease
  44. Integumentary system disease
  45. Ischemia
  46. Keratoconjunctivitis
  47. Keratopathy
  48. Musculoskeletal system disease
  49. Myasthenia gravis
  50. Myocardial infarction
  51. Myocardial ischemia
  52. Nervous system disease
  53. Neuromuscular junction disease
  54. Omenn syndrome
  55. Opportunistic mycosis
  56. Oral candidiasis
  57. Pancreas disease
  58. Parathyroid gland disease
  59. Pernicious anemia
  60. Systemic mycosis
  61. Teeth hard tissue disease
  62. Thymoma
  63. Thymus cancer
  64. Thyroid gland disease
  65. Thyroiditis
  66. Vascular disease
  67. Vitiligo

Stage Associations

This gene is associated with the following stages: