History:STAGE:Pluripotency    STAGE:Cortical Specification    STAGE:Upper Layers    GENE:PBX1    GENE:EMP2    

Cluster 42

Average behavior of genes in this cluster.

Stage Associations

This cluster is associated with 2 stages.

Gene List

This cluster contains 312 genes. Scroll for more results...

Disease Associations

This cluster is associated with the following diseases. Clicking on the disease will take you to the disease ontology entry for that disease.

This cluster is associated with 13 diseases.

Kegg Pathway Associations

This cluster is enriched for 5 KEGG pathways. Scroll to view entire list.
  1. Cell cycle
  2. Oocyte meiosis
  3. p53 signaling pathway
  4. Progesterone-mediated oocyte maturation
  5. RNA transport

Gene Ontology Associations

This cluster is associated with 379 categories. Scroll for more results.
  1. adenyl nucleotide binding
  2. adenyl ribonucleotide binding
  3. anaphase-promoting complex
  4. anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
  5. antigen processing and presentation of exogenous peptide antigen via MHC class I
  6. antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
  7. aromatic compound biosynthetic process
  8. ATP binding
  9. ATP-dependent chromatin remodeling
  10. ATP-dependent DNA helicase activity
  11. ATP-dependent helicase activity
  12. ATPase activity
  13. ATPase activity, coupled
  14. binding
  15. biological regulation
  16. biological_process
  17. biosynthetic process
  18. Cajal body
  19. catalytic activity
  20. catalytic step 2 spliceosome
  21. cell
  22. cell cycle
  23. cell cycle arrest
  24. cell cycle checkpoint
  25. cell cycle phase
  26. cell cycle process
  27. cell division
  28. cell part
  29. cellular aromatic compound metabolic process
  30. cellular biosynthetic process
  31. cellular component assembly
  32. cellular component biogenesis
  33. cellular component organization
  34. cellular component organization or biogenesis
  35. cellular macromolecular complex assembly
  36. cellular macromolecule biosynthetic process
  37. cellular macromolecule catabolic process
  38. cellular macromolecule metabolic process
  39. cellular metabolic process
  40. cellular nitrogen compound metabolic process
  41. cellular process
  42. cellular process involved in reproduction
  43. cellular protein catabolic process
  44. cellular response to cytokine stimulus
  45. cellular response to stimulus
  46. cellular response to stress
  47. cellular_component
  48. centriole replication
  49. centrosome
  50. centrosome cycle
  51. centrosome duplication
  52. centrosome organization
  53. chromatin
  54. chromosomal part
  55. chromosome
  56. chromosome condensation
  57. chromosome organization
  58. chromosome segregation
  59. chromosome, centromeric region
  60. chromosome, telomeric region
  61. condensed chromosome
  62. condensed chromosome kinetochore
  63. condensed chromosome outer kinetochore
  64. condensed chromosome, centromeric region
  65. condensed nuclear chromosome
  66. condensed nuclear chromosome, centromeric region
  67. cullin-RING ubiquitin ligase complex
  68. cytokine-mediated signaling pathway
  69. cytoplasm
  70. cytoplasmic part
  71. cytoskeletal part
  72. cytoskeleton
  73. cytoskeleton organization
  74. cytosol
  75. DNA binding
  76. DNA catabolic process, exonucleolytic
  77. DNA conformation change
  78. DNA damage checkpoint
  79. DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
  80. DNA double-strand break processing
  81. DNA helicase activity
  82. DNA integrity checkpoint
  83. DNA metabolic process
  84. DNA packaging
  85. DNA recombination
  86. DNA repair
  87. DNA replication
  88. DNA replication checkpoint
  89. DNA replication initiation
  90. DNA secondary structure binding
  91. DNA strand elongation
  92. DNA strand elongation involved in DNA replication
  93. DNA strand renaturation
  94. DNA-dependent ATPase activity
  95. DNA-dependent DNA replication
  96. DNA-dependent transcription, termination
  97. double-strand break repair
  98. double-strand break repair via homologous recombination
  99. double-stranded DNA specific exodeoxyribonuclease activity
  100. envelope
  101. establishment of RNA localization
  102. exodeoxyribonuclease activity
  103. exodeoxyribonuclease activity, producing 5'-phosphomonoesters
  104. exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
  105. flap endonuclease activity
  106. G1/S transition of mitotic cell cycle
  107. G2 phase
  108. G2 phase of mitotic cell cycle
  109. G2/M transition checkpoint
  110. G2/M transition DNA damage checkpoint
  111. G2/M transition of mitotic cell cycle
  112. gene expression
  113. helicase activity
  114. heterocycle biosynthetic process
  115. heterocycle metabolic process
  116. heterocyclic compound binding
  117. histone exchange
  118. hydrolase activity
  119. hydrolase activity, acting on acid anhydrides
  120. hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
  121. inner cell mass cell proliferation
  122. interphase
  123. interphase of mitotic cell cycle
  124. intracellular
  125. intracellular membrane-bounded organelle
  126. intracellular non-membrane-bounded organelle
  127. intracellular organelle
  128. intracellular organelle lumen
  129. intracellular organelle part
  130. intracellular part
  131. kinetochore
  132. Ku70:Ku80 complex
  133. lateral element
  134. LRR domain binding
  135. M phase
  136. M phase of meiotic cell cycle
  137. M phase of mitotic cell cycle
  138. M/G1 transition of mitotic cell cycle
  139. macromolecular complex
  140. macromolecular complex assembly
  141. macromolecular complex subunit organization
  142. macromolecule biosynthetic process
  143. macromolecule catabolic process
  144. macromolecule metabolic process
  145. meiosis
  146. meiotic cell cycle
  147. membrane-bounded organelle
  148. membrane-enclosed lumen
  149. metabolic process
  150. microtubule cytoskeleton
  151. microtubule cytoskeleton organization
  152. microtubule organizing center
  153. microtubule organizing center organization
  154. microtubule-based process
  155. mitochondrial ATP synthesis coupled proton transport
  156. mitochondrial ribosome
  157. mitosis
  158. mitotic cell cycle
  159. mitotic cell cycle checkpoint
  160. mitotic cell cycle DNA replication checkpoint
  161. mitotic cell cycle G1/S transition checkpoint
  162. mitotic cell cycle G1/S transition DNA damage checkpoint
  163. mitotic cell cycle spindle assembly checkpoint
  164. mitotic cell cycle spindle checkpoint
  165. mitotic metaphase/anaphase transition
  166. mitotic prometaphase
  167. mitotic recombination
  168. mitotic sister chromatid segregation
  169. modification-dependent macromolecule catabolic process
  170. modification-dependent protein catabolic process
  171. molecular_function
  172. mRNA 3'-end processing
  173. mRNA export from nucleus
  174. mRNA metabolic process
  175. mRNA processing
  176. mRNA splicing, via spliceosome
  177. mRNA transport
  178. multi-organism cellular process
  179. ncRNA metabolic process
  180. negative regulation of biological process
  181. negative regulation of cell cycle
  182. negative regulation of cell cycle process
  183. negative regulation of cellular process
  184. negative regulation of cellular protein metabolic process
  185. negative regulation of DNA recombination
  186. negative regulation of G2/M transition of mitotic cell cycle
  187. negative regulation of ligase activity
  188. negative regulation of macromolecule metabolic process
  189. negative regulation of mitosis
  190. negative regulation of mitotic metaphase/anaphase transition
  191. negative regulation of nuclear division
  192. negative regulation of protein ubiquitination
  193. negative regulation of ubiquitin-protein ligase activity
  194. negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  195. nitrogen compound metabolic process
  196. non-membrane-bounded organelle
  197. non-recombinational repair
  198. nuclear body
  199. nuclear centromeric heterochromatin
  200. nuclear chromosome
  201. nuclear chromosome part
  202. nuclear division
  203. nuclear envelope
  204. nuclear export
  205. nuclear lumen
  206. nuclear matrix
  207. nuclear membrane
  208. nuclear part
  209. nuclear periphery
  210. nuclear pore
  211. nuclear pore complex assembly
  212. nuclear pore organization
  213. nuclear pore outer ring
  214. nuclear speck
  215. nuclear transport
  216. nuclear ubiquitin ligase complex
  217. nuclease activity
  218. nucleic acid binding
  219. nucleic acid metabolic process
  220. nucleic acid transport
  221. nucleobase-containing compound biosynthetic process
  222. nucleobase-containing compound metabolic process
  223. nucleobase-containing compound transport
  224. nucleocytoplasmic transport
  225. nucleolus
  226. nucleoplasm
  227. nucleoplasm part
  228. nucleoside binding
  229. nucleoside phosphate binding
  230. nucleoside-triphosphatase activity
  231. nucleotide binding
  232. nucleus
  233. nucleus organization
  234. organellar ribosome
  235. organelle
  236. organelle envelope
  237. organelle fission
  238. organelle lumen
  239. organelle organization
  240. organelle part
  241. organic cyclic compound binding
  242. organic cyclic compound metabolic process
  243. organic substance biosynthetic process
  244. organic substance metabolic process
  245. PML body
  246. pore complex
  247. pore complex assembly
  248. positive regulation of cell cycle arrest
  249. positive regulation of cell cycle process
  250. positive regulation of ligase activity
  251. positive regulation of protein ubiquitination
  252. positive regulation of ubiquitin-protein ligase activity
  253. positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  254. postreplication repair
  255. primary metabolic process
  256. proteasomal protein catabolic process
  257. proteasomal ubiquitin-dependent protein catabolic process
  258. proteasome complex
  259. proteasome core complex
  260. proteasome core complex, alpha-subunit complex
  261. protein binding
  262. protein catabolic process
  263. protein complex
  264. protein import into nucleus, docking
  265. protein modification by small protein conjugation
  266. protein modification by small protein conjugation or removal
  267. protein polyubiquitination
  268. protein ubiquitination
  269. protein-DNA complex subunit organization
  270. proteolysis involved in cellular protein catabolic process
  271. purine NTP-dependent helicase activity
  272. purine nucleoside binding
  273. purine nucleotide binding
  274. purine ribonucleoside binding
  275. purine ribonucleoside triphosphate binding
  276. purine ribonucleotide binding
  277. pyrophosphatase activity
  278. recombinational repair
  279. regulation of biological process
  280. regulation of cell cycle
  281. regulation of cell cycle arrest
  282. regulation of cell cycle process
  283. regulation of cellular amine metabolic process
  284. regulation of cellular amino acid metabolic process
  285. regulation of cellular macromolecule biosynthetic process
  286. regulation of cellular metabolic process
  287. regulation of cellular process
  288. regulation of centrosome cycle
  289. regulation of chromosome segregation
  290. regulation of DNA metabolic process
  291. regulation of DNA recombination
  292. regulation of DNA replication
  293. regulation of DNA-dependent DNA replication
  294. regulation of gene expression
  295. regulation of glucose transport
  296. regulation of interphase of mitotic cell cycle
  297. regulation of ligase activity
  298. regulation of macromolecule metabolic process
  299. regulation of metabolic process
  300. regulation of microtubule-based process
  301. regulation of mitosis
  302. regulation of mitotic cell cycle
  303. regulation of mitotic metaphase/anaphase transition
  304. regulation of mRNA processing
  305. regulation of mRNA splicing, via spliceosome
  306. regulation of nitrogen compound metabolic process
  307. regulation of nuclear division
  308. regulation of nucleobase-containing compound metabolic process
  309. regulation of organelle organization
  310. regulation of primary metabolic process
  311. regulation of protein ubiquitination
  312. regulation of RNA splicing
  313. regulation of sister chromatid cohesion
  314. regulation of spindle checkpoint
  315. regulation of ubiquitin-protein ligase activity
  316. regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  317. replication fork
  318. response to cytokine stimulus
  319. response to DNA damage stimulus
  320. response to ionizing radiation
  321. response to radiation
  322. response to stress
  323. ribonucleoprotein complex
  324. ribonucleoprotein complex assembly
  325. ribonucleoprotein complex biogenesis
  326. ribonucleoprotein complex subunit organization
  327. ribonucleoside binding
  328. ribonucleotide binding
  329. RNA 3'-end processing
  330. RNA binding
  331. RNA export from nucleus
  332. RNA localization
  333. RNA metabolic process
  334. RNA processing
  335. RNA splicing
  336. RNA splicing, via transesterification reactions
  337. RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
  338. RNA transport
  339. S phase
  340. S phase of mitotic cell cycle
  341. signal transduction involved in cell cycle checkpoint
  342. signal transduction involved in DNA damage checkpoint
  343. signal transduction involved in DNA integrity checkpoint
  344. signal transduction involved in G1/S transition checkpoint
  345. signal transduction involved in mitotic cell cycle checkpoint
  346. signal transduction involved in mitotic cell cycle G1/S checkpoint
  347. signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
  348. single-organism cellular process
  349. single-organism process
  350. single-stranded DNA binding
  351. sister chromatid cohesion
  352. sister chromatid segregation
  353. small conjugating protein ligase binding
  354. small nuclear ribonucleoprotein complex
  355. spindle
  356. spindle assembly checkpoint
  357. spindle checkpoint
  358. spindle organization
  359. spindle pole
  360. spliceosomal complex
  361. spliceosomal complex assembly
  362. spliceosomal snRNP assembly
  363. structural constituent of nuclear pore
  364. structure-specific DNA binding
  365. telomere maintenance
  366. telomere maintenance via recombination
  367. telomere maintenance via semi-conservative replication
  368. telomere organization
  369. termination of RNA polymerase II transcription
  370. threonine-type endopeptidase activity
  371. threonine-type peptidase activity
  372. transcription, DNA-dependent
  373. translesion synthesis
  374. U12-type spliceosomal complex
  375. U2 snRNP
  376. ubiquitin ligase complex
  377. ubiquitin protein ligase binding
  378. ubiquitin-dependent protein catabolic process
  379. viral reproduction