History:GENE:SLC29A1    GENE:ZNF35    GENE:ACE    

Gene Expression: HFE

Gene Data

  • Gene Symbol: HFE
  • Gene ID: 3077
  • Synonyms: HFE1, HH, HLA-H, MVCD7, TFQTL2
  • Description: hemochromatosis
  • Database Refs: HGNC:4886, MIM:613609, Ensembl:ENSG00000010704, HPRD:01993, Vega:OTTHUMG00000016348
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 0 out of 9 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 77 diseases, scroll to view all:
  1. Alpha 1-antitrypsin deficiency
  2. Anemia
  3. Arthritis
  4. Arthropathy
  5. Atransferrinemia
  6. Beta thalassemia
  7. Bone disease
  8. Bone inflammation disease
  9. Cancer
  10. Carbohydrate metabolism disease
  11. Cardiovascular system disease
  12. Central nervous system disease
  13. Dermatitis
  14. Diabetes mellitus
  15. Disease
  16. Disease by infectious agent
  17. Disease of anatomical entity
  18. Disease of cellular proliferation
  19. Disease of mental health
  20. Disease of metabolism
  21. Endocrine pancreas disease
  22. Endocrine system disease
  23. Fatty liver
  24. Gastrointestinal system cancer
  25. Gastrointestinal system disease
  26. Genetic disease
  27. Genetic disorder
  28. Glucose metabolism disease
  29. Gonadal disease
  30. Heart disease
  31. Hematopoietic system disease
  32. Hemochromatosis
  33. Hemosiderosis
  34. Hepatic porphyria
  35. Hepatitis
  36. Hepatitis C
  37. Hepatobiliary disease
  38. Hepatocellular carcinoma
  39. Hypogonadism
  40. Impotence
  41. Inborn errors metal metabolism
  42. Inborn errors of metabolism
  43. Integumentary system disease
  44. Interstitial lung disease
  45. Iron deficiency anemia
  46. Iron metabolism disease
  47. Lipid metabolism disease
  48. Liver cancer
  49. Liver carcinoma
  50. Liver cirrhosis
  51. Liver disease
  52. Medical disorder
  53. Microcytic anemia
  54. Mineral metabolism disease
  55. Monogenic disease
  56. Musculoskeletal system disease
  57. Nervous system disease
  58. Neurodegenerative disease
  59. Nutrition disease
  60. Nutritional deficiency disease
  61. Organ system cancer
  62. Pancreas disease
  63. Penile disease
  64. Pneumoconiosis
  65. Porphyria
  66. Porphyria cutanea tarda
  67. Reproductive system disease
  68. Sexual disease
  69. Sexual dysfunction
  70. Sideroblastic anemia
  71. Siderosis
  72. Skin disease
  73. Thalassemia
  74. Viral hepatitis
  75. Viral infectious disease
  76. Wilson disease
  77. X-linked sideroblastic anemia

Stage Associations

This gene is associated with the following stages: