Gene Expression: HMGCL

Gene Data

  • Gene Symbol: HMGCL
  • Gene ID: 3155
  • Synonyms: HL
  • Description: 3-hydroxymethyl-3-methylglutaryl-CoA lyase
  • Database Refs: HGNC:5005, MIM:613898, Ensembl:ENSG00000117305, HPRD:02003, Vega:OTTHUMG00000002963
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 2 out of 13 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 28 diseases, scroll to view all:
  1. Argininosuccinic aciduria
  2. beta-ketothiolase deficiency
  3. Biotinidase deficiency
  4. Carbohydrate metabolism disease
  5. Disease of metabolism
  6. Endocrine pancreas disease
  7. Endocrine system disease
  8. Gastrointestinal system disease
  9. Genetic disorder
  10. Glucose metabolism disease
  11. Holocarboxylase synthetase deficiency
  12. Homocystinuria
  13. Hypoglycemia
  14. Inborn errors of amino acid metabolism
  15. Inborn errors of metabolism
  16. Inborn metabolic brain disease
  17. Isovaleric acidemia
  18. Maple syrup urine disease
  19. Metabolic brain disease
  20. Multiple carboxylase deficiency
  21. Ornithine carbamoyltransferase deficienc
  22. Pancreas disease
  23. Phenylketonuria
  24. Propionic acidemia
  25. Reye syndrome
  26. Sulfuraminoacidemia
  27. Tyrosinemia
  28. VACTERL association

Stage Associations

This gene is associated with the following stages: