Gene Expression: APP

Gene Data

  • Gene Symbol: APP
  • Gene ID: 351
  • Synonyms: AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2
  • Description: amyloid beta (A4) precursor protein
  • Database Refs: HGNC:620, MIM:104760, Ensembl:ENSG00000142192, HPRD:00100, Vega:OTTHUMG00000078438
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 4 out of 22 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 55 diseases, scroll to view all:
  1. Actinobacillosis
  2. Adenocarcinoma
  3. Alzheimer's disease
  4. Amyloidosis
  5. Atypical choroid plexus papilloma
  6. Basal ganglia disease
  7. Brain disease
  8. Cancer
  9. Carcinoma
  10. Cardiovascular system disease
  11. Cell type cancer
  12. Central nervous system disease
  13. Cerebral amyloid angiopathy
  14. Cerebral arterial disease
  15. Cerebrovascular disease
  16. Chromosomal disease
  17. Cognitive disease
  18. Dementia
  19. Disease
  20. Disease of anatomical entity
  21. Disease of cellular proliferation
  22. Disease of mental health
  23. Disease of metabolism
  24. Down syndrome
  25. Frontotemporal dementia
  26. Gastrointestinal system cancer
  27. Genetic disease
  28. Inclusion body myositis
  29. Intracranial arterial disease
  30. Intracranial arteriosclerosis
  31. Ischemia
  32. Lung cancer
  33. Lung carcinoma
  34. Meningoencephalitis
  35. Monogenic disease
  36. Muscle tissue disease
  37. Muscular disease
  38. Myopathy
  39. Myositis
  40. Neoplasm of autonomic nervous system
  41. Nervous system disease
  42. Neuroblastoma
  43. Neurodegenerative disease
  44. non-small cell lung carcinoma
  45. Organ system cancer
  46. Penile cancer
  47. Peripheral nervous system neoplasm
  48. Respiratory system cancer
  49. Skin atrophy
  50. Squamous cell carcinoma
  51. Tauopathy
  52. Toxic encephalopathy
  53. Urinary tract cancer
  54. Vascular dementia
  55. Vascular disease

Stage Associations

This gene is associated with the following stages: