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Gene Expression: SERPINE1

Gene Data

  • Gene Symbol: SERPINE1
  • Gene ID: 5054
  • Synonyms: PAI, PAI-1, PAI1, PLANH1
  • Description: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Database Refs: HGNC:8583, MIM:173360, Ensembl:ENSG00000106366, HPRD:01418, Vega:OTTHUMG00000157107
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 0 out of 13 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 101 diseases, scroll to view all:
  1. Acute myocardial infarction
  2. Adult respiratory distress syndrome
  3. Aneurysm
  4. Arterial occlusive disease
  5. Arteriopathy
  6. Arteriosclerosis
  7. Arteriosclerotic cardiovascular disease
  8. Atherosclerosis
  9. Blood coagulation disease
  10. Brain disease
  11. Brain infarction
  12. Breast cancer
  13. Cancer
  14. Carbohydrate metabolism disease
  15. Cardiovascular system disease
  16. Cell type cancer
  17. Central nervous system disease
  18. Cerebral infarction
  19. Cerebrovascular accident
  20. Cerebrovascular disease
  21. Chronic kidney failure
  22. Coronary arteriosclerosis
  23. Coronary heart disease
  24. Coronary restenosis
  25. Coronary stenosis
  26. Coronary thrombosis
  27. Diabetes mellitus
  28. Diabetes mellitus type 2
  29. Diabetic retinopathy
  30. Disease
  31. Disease of anatomical entity
  32. Disease of cellular proliferation
  33. Disease of metabolism
  34. Disseminated intravascular coagulation
  35. End stage renal failure
  36. Endocrine pancreas disease
  37. Endocrine system disease
  38. Essential hypertension
  39. Extrinsic cardiomyopathy
  40. Eye and adnexa disease
  41. Eye disease
  42. Fatty liver
  43. Female reproductive system disease
  44. Gastrointestinal system cancer
  45. Gastrointestinal system disease
  46. Genitourinary cancer
  47. Globe disease
  48. Glomerulonephritis
  49. Glucose intolerance
  50. Glucose metabolism disease
  51. Heart disease
  52. Heart failure
  53. Hematopoietic system disease
  54. Hemorrhagic disease
  55. Hepatobiliary disease
  56. Hypercholesterolemia
  57. Hyperglycemia
  58. Hyperhomocysteinemia
  59. Hyperinsulinism
  60. Hypertension
  61. Inborn errors of amino acid metabolism
  62. Intermediate coronary syndrome
  63. Interstitial lung disease
  64. Ischemia
  65. Ischemic bone disease
  66. Kidney disease
  67. Kidney failure
  68. Lipid metabolism disease
  69. Lower respiratory tract disease
  70. Lung disease
  71. Musculoskeletal system disease
  72. Myocardial infarction
  73. Myocardial ischemia
  74. Nephritis
  75. Nephrosclerosis
  76. Nervous system disease
  77. Organ system cancer
  78. Osteonecrosis
  79. Pancreas disease
  80. Polycystic ovary syndrome
  81. pre-eclampsia
  82. Pregnancy complication
  83. Pregnancy disease
  84. Proteinuria
  85. Pulmonary embolism
  86. Pulmonary fibrosis
  87. Reproductive system disease
  88. Respiratory failure
  89. Respiratory system disease
  90. Retinal disease
  91. Retinal vascular disease
  92. Sensory system disease
  93. Spontaneous abortion
  94. Syndrome
  95. Thoracic cancer
  96. Thrombophilia
  97. Ureteral disease
  98. Ureteral obstruction
  99. Urinary system disease
  100. Urinary tract obstruction
  101. Vascular disease

Stage Associations

This gene is associated with the following stages: