Gene Expression: PDE4A

Gene Data

  • Gene Symbol: PDE4A
  • Gene ID: 5141
  • Synonyms: DPDE2, PDE4, PDE46
  • Description: phosphodiesterase 4A, cAMP-specific
  • Database Refs: HGNC:8780, MIM:600126, Ensembl:ENSG00000065989, HPRD:02527
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 2 out of 23 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters: No Clusters were found

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 154 diseases, scroll to view all:
  1. Achromatopsia
  2. Acrodysostosis
  3. Allergic asthma
  4. Arterial occlusive disease
  5. Arteriopathy
  6. Arteriosclerosis
  7. Arteriosclerotic cardiovascular disease
  8. Arthritis
  9. Asthma
  10. Atherosclerosis
  11. Atopic dermatitis
  12. Axonal neuropathy
  13. Bacterial infectious disease
  14. Blindness
  15. Bone disease
  16. Bone inflammation disease
  17. Brain disease
  18. Bronchial disease
  19. Cancer
  20. Carbohydrate metabolism disease
  21. Cardiovascular system disease
  22. Central nervous system disease
  23. Cerebrovascular accident
  24. Cerebrovascular disease
  25. Cholera
  26. Chronic obstructive pulmonary disease
  27. Chronic pulmonary heart disease
  28. Cognitive disease
  29. Collagen disease
  30. Congenital heart defect
  31. Congestive heart failure
  32. Connective tissue disease
  33. Cor pulmonale
  34. Coronary heart disease
  35. Cranial nerve disease
  36. Demyelinating disease
  37. Dermatitis
  38. Diabetes mellitus
  39. Diarrhea
  40. Dilated cardiomyopathy
  41. Disease
  42. Disease by infectious agent
  43. Disease of anatomical entity
  44. Disease of cellular proliferation
  45. Disease of mental health
  46. Disease of metabolism
  47. Dyspepsia
  48. Endocrine pancreas disease
  49. Endocrine system disease
  50. Eosinophilia
  51. Extrinsic cardiomyopathy
  52. Eye and adnexa disease
  53. Eye disease
  54. Functional gastric disease
  55. Fundus dystrophy
  56. Gastrointestinal system disease
  57. Genetic disease
  58. Genitourinary cancer
  59. Globe disease
  60. Glucose metabolism disease
  61. Gonadal disease
  62. Heart disease
  63. Heart failure
  64. Hematologic cancer
  65. Hepatobiliary disease
  66. Hypersensitivity reaction disease
  67. Hypersensitivity reaction type II diseas
  68. Hypertension
  69. Hypoactive sexual desire disease
  70. Hypogonadism
  71. Immune system disease
  72. Impotence
  73. Inhibited female orgasm
  74. Integumentary system disease
  75. Intermittent claudication
  76. Intrinsic cardiomyopathy
  77. Ischemia
  78. Ischemic optic neuropathy
  79. Kidney disease
  80. Leber congenital amaurosis
  81. Lipid metabolism disease
  82. Liver disease
  83. Low compliance bladder
  84. Lower respiratory tract disease
  85. Lung disease
  86. Male reproductive organ cancer
  87. Male reproductive system disease
  88. Medical disorder
  89. Monogenic disease
  90. Multiple sclerosis
  91. Musculoskeletal system disease
  92. Myocardial infarction
  93. Myocardial ischemia
  94. Nasal cavity disease
  95. Nasopharyngeal disease
  96. Nasopharyngitis
  97. Neoplasm of autonomic nervous system
  98. Nephrogenic diabetes insipidus
  99. Nervous system cancer
  100. Nervous system disease
  101. Neuroblastoma
  102. Neurodegenerative disease
  103. Neuropathy
  104. Niemann-Pick disease
  105. Night blindness
  106. non-langerhans-cell histiocytosis
  107. Nose disease
  108. Obstructive lung disease
  109. Ocular hypotension
  110. Optic nerve disease
  111. Organ system cancer
  112. Pancreas disease
  113. Patent ductus arteriosus
  114. Penile disease
  115. Peripheral nervous system neoplasm
  116. Peripheral vascular disease
  117. Persistent fetal circulation syndrome
  118. Peyronie's disease
  119. Physical disorder
  120. Portal hypertension
  121. Premature ejaculation
  122. Priapism
  123. Primary bacterial infectious disease
  124. Primary pulmonary hypertension
  125. Prostate cancer
  126. Prostate disease
  127. Psychosexual disease
  128. Psychotic disease
  129. Pulmonary edema
  130. Pulmonary hypertension
  131. Pulmonary venoocclusive disease
  132. Raynaud disease
  133. Reproductive organ cancer
  134. Reproductive system disease
  135. Respiratory failure
  136. Respiratory system disease
  137. Retinal degeneration
  138. Retinal disease
  139. Retinitis pigmentosa
  140. Rheumatic disease
  141. Rhinitis
  142. Schizophrenia
  143. Scleroderma
  144. Sensory system disease
  145. Sexual disease
  146. Sexual dysfunction
  147. Skin disease
  148. Stomach disease
  149. Systemic scleroderma
  150. Upper respiratory tract disease
  151. Urinary system disease
  152. Vascular disease
  153. Vasculogenic impotence
  154. Visual pathway disease

Stage Associations

This gene is associated with the following stages: No Stages were found