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Gene Expression: OPTN

Gene Data

  • Gene Symbol: OPTN
  • Gene ID: 10133
  • Synonyms: ALS12, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP
  • Description: optineurin
  • Database Refs: HGNC:17142, MIM:602432, Ensembl:ENSG00000123240, HPRD:03891, Vega:OTTHUMG00000017690
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 1 out of 19 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 41 diseases, scroll to view all:
  1. Acute closed-angle glaucoma
  2. Amyotrophic lateral sclerosis
  3. angle-closure glaucoma
  4. Anterior horn cell disease
  5. Blindness
  6. Borderline glaucoma
  7. Central nervous system disease
  8. Central nervous system hereditary degene
  9. Disease
  10. Disease of anatomical entity
  11. Exfoliation syndrome
  12. Eye and adnexa disease
  13. Eye disease
  14. Glaucoma
  15. Globe disease
  16. Hepatobiliary disease
  17. Hyperostosis
  18. Juvenile glaucoma
  19. Leber hereditary optic neuropathy
  20. Liver disease
  21. locked-in syndrome
  22. Low tension glaucoma
  23. Motor neuron disease
  24. Muscle tissue disease
  25. Muscular disease
  26. Musculoskeletal system disease
  27. Myopathy
  28. Nervous system disease
  29. Neurodegenerative disease
  30. Neuromuscular disease
  31. Neuropathy
  32. Ocular hypertension
  33. open-angle glaucoma
  34. Paget's disease of bone
  35. Phacogenic glaucoma
  36. Primary angle-closure glaucoma
  37. Primary congenital glaucoma
  38. Primary open anle glaucoma
  39. Retinal degeneration
  40. Retinal disease
  41. Sensory system disease

Stage Associations

This gene is associated with the following stages: