Gene Expression: AKR1B1

Gene Data

  • Gene Symbol: AKR1B1
  • Gene ID: 231
  • Synonyms: ADR, ALDR1, ALR2, AR
  • Description: aldo-keto reductase family 1, member B1 (aldose reductase)
  • Database Refs: HGNC:381, MIM:103880, Ensembl:ENSG00000085662, HPRD:00071, Vega:OTTHUMG00000155322
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 1 out of 10 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 66 diseases, scroll to view all:
  1. Autonomic nervous system disease
  2. Autonomic neuropathy
  3. Background diabetic retinopathy
  4. Blindness
  5. Breast cancer
  6. Cancer
  7. Carbohydrate metabolism disease
  8. Cardiovascular system disease
  9. Cataract
  10. Diabetes mellitus
  11. Diabetes mellitus type 1
  12. Diabetes mellitus type 2
  13. Diabetic autonomic neuropathy
  14. Diabetic cataract
  15. Diabetic neuropathy
  16. Diabetic polyneuropathy
  17. Diabetic retinopathy
  18. Disease
  19. Disease by infectious agent
  20. Disease of anatomical entity
  21. Disease of cellular proliferation
  22. Disease of metabolism
  23. Endocrine pancreas disease
  24. Endocrine system disease
  25. Eye and adnexa disease
  26. Eye disease
  27. Galactosemia
  28. Gastrointestinal system cancer
  29. Gastrointestinal system disease
  30. Globe disease
  31. Glucose metabolism disease
  32. Hepatitis
  33. Hepatitis B
  34. Hepatobiliary disease
  35. Hyperglycemia
  36. Immature cataract
  37. Inborn errors carbohydrate metabolism
  38. Inborn metabolic brain disease
  39. Ischemia
  40. Keratopathy
  41. Kidney disease
  42. Kidney failure
  43. Lens disease
  44. Liver cancer
  45. Liver disease
  46. Mature cataract
  47. Metabolic brain disease
  48. Nervous system disease
  49. Neuroaxonal dystrophy
  50. Neuropathy
  51. Organ system cancer
  52. Pancreas disease
  53. Peripheral nervous system disease
  54. Peripheral neuropathy
  55. Polyneuropathy
  56. Proliferative diabetic retinopathy
  57. Proteinuria
  58. Retinal disease
  59. Retinal vascular disease
  60. Senile cataract
  61. Sensory peripheral neuropathy
  62. Sensory system disease
  63. Thoracic cancer
  64. Urinary system disease
  65. Vascular disease
  66. Viral infectious disease

Stage Associations

This gene is associated with the following stages: