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Gene Expression: PSEN1

Gene Data

  • Gene Symbol: PSEN1
  • Gene ID: 5663
  • Synonyms: AD3, FAD, PS-1, PS1, S182
  • Description: presenilin 1
  • Database Refs: HGNC:9508, MIM:104311, Ensembl:ENSG00000080815, HPRD:00087, Vega:OTTHUMG00000141279
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 1 out of 16 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 35 diseases, scroll to view all:
  1. Alzheimer's disease
  2. Amyloidosis
  3. Aphasia
  4. Basal ganglia disease
  5. Brain disease
  6. Central nervous system disease
  7. Cerebral amyloid angiopathy
  8. Cerebral arterial disease
  9. Cerebral degeneration
  10. Cerebrovascular disease
  11. Cognitive disease
  12. Communication disease
  13. Cri-Du-Chat syndrome
  14. Dementia
  15. Disease
  16. Disease of anatomical entity
  17. Disease of mental health
  18. Disease of metabolism
  19. Down syndrome
  20. Frontotemporal dementia
  21. Intracranial arterial disease
  22. Intracranial arteriosclerosis
  23. Kluver-Bucy syndrome
  24. Language disease
  25. Leukodystrophy
  26. Lewy body dementia
  27. Neoplasm of autonomic nervous system
  28. Nervous system cancer
  29. Nervous system disease
  30. Neuroblastoma
  31. Neurodegenerative disease
  32. Peripheral nervous system neoplasm
  33. Tauopathy
  34. Toxic encephalopathy
  35. Vascular dementia

Stage Associations

This gene is associated with the following stages: