Gene Expression: GPX4

Gene Data

  • Gene Symbol: GPX4
  • Gene ID: 2879
  • Synonyms: GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx
  • Description: glutathione peroxidase 4
  • Database Refs: HGNC:4556, MIM:138322, Ensembl:ENSG00000167468, HPRD:11819, Vega:OTTHUMG00000181874
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 3 out of 9 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters: No Clusters were found

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 169 diseases, scroll to view all:
  1. Acute myocardial infarction
  2. Acute pancreatitis
  3. Alzheimer's disease
  4. Amyotrophic lateral sclerosis
  5. Anemia
  6. Anterior horn cell disease
  7. Anthracosis
  8. Arterial occlusive disease
  9. Arteriopathy
  10. Arteriosclerosis
  11. Arteriosclerotic cardiovascular disease
  12. Arthritis
  13. Asthma
  14. Atherosclerosis
  15. Atrophic muscular disease
  16. Basal ganglia disease
  17. Bile duct disease
  18. Biliary tract disease
  19. Bone disease
  20. Bone inflammation disease
  21. Brain disease
  22. Brain infarction
  23. Breast cancer
  24. Breast disease
  25. Bronchial disease
  26. Bronchopulmonary dysplasia
  27. Cancer
  28. Carbohydrate metabolism disease
  29. Carcinoma
  30. Cardiovascular system disease
  31. Cataract
  32. Cell type cancer
  33. Central nervous system disease
  34. Central nervous system hereditary degene
  35. Cerebral artery occlusion
  36. Cerebral infarction
  37. Cerebrovascular accident
  38. Cerebrovascular disease
  39. Cholestasis
  40. Chromosomal disease
  41. Chronic kidney failure
  42. Chronic obstructive pulmonary disease
  43. Cognitive disease
  44. Colon cancer
  45. Colorectal cancer
  46. Congenital hemolytic anemia
  47. Coronary heart disease
  48. Dementia
  49. Diabetes mellitus
  50. Diabetic cataract
  51. Disease
  52. Disease by infectious agent
  53. Disease of anatomical entity
  54. Disease of cellular proliferation
  55. Disease of mental health
  56. Disease of metabolism
  57. Down syndrome
  58. End stage renal failure
  59. Endocrine pancreas disease
  60. Endocrine system disease
  61. Extrinsic cardiomyopathy
  62. Eye and adnexa disease
  63. Eye disease
  64. Fatty liver
  65. Favism
  66. Gastrointestinal system cancer
  67. Gastrointestinal system disease
  68. Genetic disease
  69. Globe disease
  70. Glucose metabolism disease
  71. Glucosephosphate dehydrogenase deficienc
  72. Goiter
  73. Heart disease
  74. Heart failure
  75. Hematologic cancer
  76. Hematopoietic system disease
  77. Hemolytic anemia
  78. Hepatitis
  79. Hepatobiliary disease
  80. Hepatocellular carcinoma
  81. Hypercholesterolemia
  82. Hyperglycemia
  83. Hypersensitivity reaction disease
  84. Hypersensitivity reaction type II diseas
  85. Hypertension
  86. Hyperthyroidism
  87. Hypothyroidism
  88. Immune system disease
  89. Inborn errors of amino acid metabolism
  90. Inborn errors of metabolism
  91. Inborn metabolic brain disease
  92. Infertility
  93. Interstitial lung disease
  94. Intestinal cancer
  95. Intestinal disease
  96. Ischemia
  97. Keshan disease
  98. Kidney disease
  99. Kidney failure
  100. Large intestine cancer
  101. Lens disease
  102. Lice infestation
  103. Lipid metabolism disease
  104. Liver cancer
  105. Liver carcinoma
  106. Liver cirrhosis
  107. Liver disease
  108. Lower respiratory tract disease
  109. Lung cancer
  110. Lung disease
  111. Male infertility
  112. Male reproductive system disease
  113. Maple syrup urine disease
  114. Mastitis
  115. Mild pre-eclampsia
  116. Monogenic disease
  117. Motor neuron disease
  118. Muscle tissue disease
  119. Muscular disease
  120. Muscular dystrophy
  121. Musculoskeletal system disease
  122. Myocardial infarction
  123. Myocardial ischemia
  124. Myopathy
  125. Nervous system disease
  126. Neurodegenerative disease
  127. Neuromuscular disease
  128. Neuropathy
  129. Normocytic anemia
  130. Nutrition disease
  131. Nutritional deficiency disease
  132. Obstructive lung disease
  133. Organ system cancer
  134. Pancreas disease
  135. Pancreatitis
  136. Parasitic ectoparasitic infectious disea
  137. Parasitic infectious disease
  138. Parasitic protozoa infectious disease
  139. Parkinson's disease
  140. Pelvic varices
  141. Phenylketonuria
  142. Pneumoconiosis
  143. pre-eclampsia
  144. Proteinuria
  145. Psychotic disease
  146. Pthirus pubis infestation
  147. Pulmonary fibrosis
  148. Reproductive system disease
  149. Respiratory failure
  150. Respiratory system cancer
  151. Respiratory system disease
  152. Retinal disease
  153. Rheumatoid arthritis
  154. Schizophrenia
  155. Senile cataract
  156. Sensory system disease
  157. Spermatic cord torsion
  158. Spinal cord ischemia
  159. Spinal cord vascular disease
  160. Tauopathy
  161. Testicular disease
  162. Thoracic cancer
  163. Thyroid gland disease
  164. Thyrotoxicosis
  165. Toxic encephalopathy
  166. Urinary system disease
  167. Vascular disease
  168. Viral infectious disease
  169. Vitiligo

Stage Associations

This gene is associated with the following stages: No Stages were found