Gene Expression: PTPN11

Gene Data

  • Gene Symbol: PTPN11
  • Gene ID: 5781
  • Synonyms: BPTP3, CFC, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2
  • Description: protein tyrosine phosphatase, non-receptor type 11
  • Database Refs: HGNC:9644, MIM:176876, Ensembl:ENSG00000179295, HPRD:01470, Vega:OTTHUMG00000134334
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 1 out of 17 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 99 diseases, scroll to view all:
  1. Acute myeloid leukemia
  2. Arthritis
  3. Astrocytoma
  4. Atrophic gastritis
  5. Autoimmune disease of endocrine system
  6. Autoimmune thyroiditis
  7. Bone disease
  8. Bone inflammation disease
  9. Bone marrow cancer
  10. Bone marrow disease
  11. Brain cancer
  12. Brain neoplasm
  13. Bubonic plague
  14. Cancer
  15. Carbohydrate metabolism disease
  16. Carcinoma
  17. Cardiovascular system disease
  18. CD45 deficiency
  19. Cell type cancer
  20. Central nervous system disease
  21. Central nervous system neoplasm
  22. Cherubism
  23. Colorectal cancer
  24. Congenital heart defect
  25. Connective tissue disease
  26. Costello syndrome
  27. Crohn's disease
  28. Cryptorchidism
  29. Cystic lymphangioma
  30. Developmental disease of mental health
  31. Diabetes mellitus
  32. Diabetes mellitus type 1
  33. Disease
  34. Disease by infectious agent
  35. Disease of anatomical entity
  36. Disease of cellular proliferation
  37. Disease of mental health
  38. Disease of metabolism
  39. Endocrine pancreas disease
  40. Endocrine system disease
  41. Gastric adenocarcinoma
  42. Gastritis
  43. Gastrointestinal system cancer
  44. Gastrointestinal system disease
  45. Genetic disease
  46. Glucose metabolism disease
  47. Goiter
  48. Graves' disease
  49. Heart disease
  50. Heart valve disease
  51. Hematologic cancer
  52. Hematopoietic system disease
  53. Hypersensitivity reaction disease
  54. Hypersensitivity reaction type II diseas
  55. Hyperthyroidism
  56. Hypertrophic cardiomyopathy
  57. Immune system disease
  58. Inflammatory bowel disease
  59. Inner ear disease
  60. Intellectual disability
  61. Intestinal cancer
  62. Intracranial neoplasm
  63. Intrinsic cardiomyopathy
  64. Juvenile myelomonocytic leukemia
  65. Lafora disease
  66. Large intestine cancer
  67. LEOPARD syndrome
  68. Leukemia
  69. Lupus erythematosus
  70. Lymphoblastic leukemia
  71. Lymphoma
  72. Medical disorder
  73. Monogenic disease
  74. Musculoskeletal system disease
  75. Myelodysplastic myeloproliferative cance
  76. Myeloid leukemia
  77. Myeloma
  78. Nervous system cancer
  79. Nervous system disease
  80. Neurodegenerative disease
  81. Neurofibromatosis
  82. Noonan syndrome
  83. Organ system cancer
  84. Pancreas disease
  85. Physical disorder
  86. Plague
  87. Progressive myoclonic epilepsy
  88. Pulmonary valve disease
  89. Pulmonary valve stenosis
  90. Rheumatoid arthritis
  91. Sensorineural hearing loss
  92. Specific developmental disease
  93. Stomach cancer
  94. Stomach carcinoma
  95. Stomach disease
  96. Systemic lupus erythematosus
  97. Thyroid gland disease
  98. Thyroiditis
  99. Thyrotoxicosis

Stage Associations

This gene is associated with the following stages: