History:GENE:CA2    GENE:APC    

Gene Expression: F2

Gene Data

  • Gene Symbol: F2
  • Gene ID: 2147
  • Synonyms: PT, RPRGL2, THPH1
  • Description: coagulation factor II (thrombin)
  • Database Refs: HGNC:3535, MIM:176930, Ensembl:ENSG00000180210, HPRD:01488, Vega:OTTHUMG00000150344
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 0 out of 14 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 252 diseases, scroll to view all:
  1. Abdominal aortic aneurysm
  2. Active peptic ulcer disease
  3. Acute kidney failure
  4. Acute myocardial infarction
  5. Alcohol abuse
  6. Alcoholic hepatitis
  7. Alcoholic liver cirrhosis
  8. Anemia
  9. Aneurysm
  10. Antiphospholipid syndrome
  11. Antithrombin III deficiency
  12. Aortic aneurysm
  13. Aortic disease
  14. Arterial occlusive disease
  15. Arteriopathy
  16. Arteriosclerosis
  17. Arteriosclerotic cardiovascular disease
  18. Arthropathy
  19. Asthma
  20. Atherosclerosis
  21. Atrial heart septal defect
  22. Autoimmune disease of gastrointestinal t
  23. Autoimmune disease of urogenital tract
  24. Autoimmune hepatitis
  25. Bacterial infectious disease
  26. Bernard-Soulier syndrome
  27. Beta thalassemia
  28. Bile duct disease
  29. Biliary atresia
  30. Biliary tract disease
  31. Blood coagulation disease
  32. Blood platelet disease
  33. Blood protein disease
  34. Bone disease
  35. Bone inflammation disease
  36. Bone marrow cancer
  37. Bone marrow disease
  38. Brain disease
  39. Brain hypoxia-Ischemia
  40. Brain infarction
  41. Brain ischemia
  42. Bronchial disease
  43. Cancer
  44. Carbohydrate metabolism disease
  45. Cardiovascular system disease
  46. Carotid artery disease
  47. Carotid artery thrombosis
  48. Cell type cancer
  49. Central nervous system disease
  50. Central retinal vein occlusion
  51. Cerebral infarction
  52. Cerebrovascular accident
  53. Cerebrovascular disease
  54. Cholangiolocellular carcinoma
  55. Cholangitis
  56. Cholestasis
  57. Chronic kidney failure
  58. Congenital afibrinogenemia
  59. Congenital heart defect
  60. Connective tissue disease
  61. Coronary arteriosclerosis
  62. Coronary heart disease
  63. Coronary thrombosis
  64. Crimean-Congo hemorrhagic fever
  65. Dengue disease
  66. Dengue hemorrhagic fever
  67. Diabetes mellitus
  68. Diarrhea
  69. Disease
  70. Disease by infectious agent
  71. Disease of anatomical entity
  72. Disease of cellular proliferation
  73. Disease of metabolism
  74. Disseminated intravascular coagulation
  75. Eclampsia
  76. Endocarditis
  77. Endocrine pancreas disease
  78. Endocrine system disease
  79. Esophageal varix
  80. Extrinsic cardiomyopathy
  81. Eye and adnexa disease
  82. Eye disease
  83. Factor V deficiency
  84. Factor VII deficiency
  85. Factor VIII deficiency
  86. Factor X deficiency
  87. Factor XI deficiency
  88. Factor XII deficiency
  89. Factor XIII deficiency
  90. Fatty liver
  91. Female reproductive system disease
  92. Gallbladder disease
  93. Gastrointestinal system cancer
  94. Gastrointestinal system disease
  95. Genetic disease
  96. Glanzmann's thrombasthenia
  97. Globe disease
  98. Glucose metabolism disease
  99. Habitual abortion
  100. Heart disease
  101. Heart failure
  102. Heart septal defect
  103. Heart valve disease
  104. HELLP syndrome
  105. Hemarthrosis
  106. Hematologic cancer
  107. Hematopoietic system disease
  108. Hemolytic anemia
  109. Hemophilia B
  110. Hemorrhagic disease
  111. Hepatic coma
  112. Hepatic encephalopathy
  113. Hepatic vascular disease
  114. Hepatic vein thrombosis
  115. Hepatitis
  116. Hepatitis A
  117. Hepatitis B
  118. Hepatitis C
  119. Hepatitis E
  120. Hepatobiliary disease
  121. Hepatocellular carcinoma
  122. Hepatorenal syndrome
  123. Hereditary hyperbilirubinemia
  124. Hypercholesterolemia
  125. Hyperhomocysteinemia
  126. Hypersensitivity reaction disease
  127. Hypersensitivity reaction type II diseas
  128. Hypersplenism
  129. Hypertension
  130. Hypoglycemia
  131. Immune system disease
  132. Inborn errors metal metabolism
  133. Inborn errors of amino acid metabolism
  134. Inborn errors of metabolism
  135. Inflammatory bowel disease
  136. Influenza
  137. Inherited blood coagulation disease
  138. Integumentary system disease
  139. Intermediate coronary syndrome
  140. Intermittent claudication
  141. Intestinal disease
  142. Intracranial embolism
  143. Intracranial hypertension
  144. Intracranial sinus thrombosis
  145. Intracranial thrombosis
  146. Ischemia
  147. Ischemic bone disease
  148. Kidney disease
  149. Kidney failure
  150. Lactic acidosis
  151. Leptospirosis
  152. Leukemia
  153. Leukocyte disease
  154. Leukopenia
  155. Lipid metabolism disease
  156. Liver cancer
  157. Liver carcinoma
  158. Liver cirrhosis
  159. Liver disease
  160. Lower respiratory tract disease
  161. Lung disease
  162. Lupus erythematosus
  163. Lymphatic system disease
  164. Marantic endocarditis
  165. Mineral metabolism disease
  166. Mitral valve disease
  167. Mitral valve stenosis
  168. Monogenic disease
  169. Musculoskeletal system disease
  170. Myeloma
  171. Myocardial infarction
  172. Myocardial ischemia
  173. Nephrosis
  174. Nephrotic syndrome
  175. Nervous system disease
  176. Newborn respiratory distress syndrome
  177. Normocytic anemia
  178. Nutrition disease
  179. Nutritional deficiency disease
  180. Obstructive jaundice
  181. Obstructive lung disease
  182. Organ system cancer
  183. Osteonecrosis
  184. Pancreas disease
  185. Pancreatitis
  186. Parasitic helminthiasis infectious disea
  187. Parasitic infectious disease
  188. Patent foramen ovale
  189. Peptic ulcer
  190. Peripheral vascular disease
  191. Peritonitis
  192. Phlebitis
  193. Placenta disease
  194. Placental abruption
  195. Placental infarction
  196. Placental necrosis
  197. Pneumonia
  198. Polycythemia
  199. Portal hypertension
  200. Portal vein thrombosis
  201. pre-eclampsia
  202. Pregnancy complication
  203. Pregnancy disease
  204. Primary bacterial infectious disease
  205. Primary biliary cirrhosis
  206. Protein C deficiency
  207. Protein S deficiency
  208. Proteinuria
  209. Prothrombin deficiency
  210. Pulmonary embolism
  211. Reproductive system disease
  212. Respiratory failure
  213. Respiratory system disease
  214. Retinal disease
  215. Retinal vascular disease
  216. Retinal vascular occlusion
  217. Retinal vein occlusion
  218. Reye syndrome
  219. Rheumatic disease of mitral valve
  220. Sagittal sinus thrombosis
  221. Schistosomiasis
  222. Sclerosing cholangitis
  223. Sensory system disease
  224. Severe pre-eclampsia
  225. Skin disease
  226. Splenic disease
  227. Splenic infarction
  228. Spontaneous abortion
  229. Substance abuse
  230. substance-related disease
  231. Syphilis
  232. Systemic lupus erythematosus
  233. Thalassemia
  234. Thrombocytopenia
  235. Thrombocytosis
  236. Thrombophilia
  237. Thrombophlebitis
  238. Thrombotic thrombocytopenic purpura
  239. Transient cerebral ischemia
  240. Ulcerative colitis
  241. Urinary system disease
  242. Urticaria
  243. Vascular disease
  244. Vascular skin disease
  245. Vasculitis
  246. Vein disease
  247. Vericose veins
  248. Viral hepatitis
  249. Viral infectious disease
  250. Vitamin K deficiency hemorrhagic disease
  251. Von Willebrand's disease
  252. Wilson disease

Stage Associations

This gene is associated with the following stages: