History:GENE:NOTCH1    

Gene Expression: NF1

Gene Data

  • Gene Symbol: NF1
  • Gene ID: 4763
  • Synonyms: NFNS, VRNF, WSS
  • Description: neurofibromin 1
  • Database Refs: HGNC:7765, MIM:613113, Ensembl:ENSG00000196712, HPRD:01203, Vega:OTTHUMG00000132871
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 19 out of 69 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 141 diseases, scroll to view all:
  1. Acoustic neuroma
  2. Aneurysm
  3. Astrocytoma
  4. Attention deficit hyperactivity disease
  5. Atypical neurofibroma
  6. Benign neoplasm
  7. Bone marrow cancer
  8. Bone marrow disease
  9. Brain cancer
  10. Brain disease
  11. Brain neoplasm
  12. Brain stem glioma
  13. Brain stem neoplasm
  14. Buphthalmos
  15. Cancer
  16. Cardiovascular system disease
  17. Cell type cancer
  18. Cellular schwannoma
  19. Central nervous system cancer
  20. Central nervous system disease
  21. Central nervous system neoplasm
  22. Cerebellar astrocytoma
  23. Cerebral arterial disease
  24. Cerebral degeneration
  25. Chiasmal syndrome
  26. Choroid cancer
  27. Connective tissue neoplasm
  28. Cranial nerve disease
  29. Cranial nerve neoplasm
  30. Developmental disease of mental health
  31. Disease
  32. Disease of anatomical entity
  33. Disease of cellular proliferation
  34. Disease of mental health
  35. Duodenal somatostatinoma
  36. Elephantiasis
  37. Embryonal cancer
  38. Exophthalmos
  39. Eye and adnexa disease
  40. Eye disease
  41. Fibromuscular dysplasia
  42. Fibrosarcoma
  43. Fibrous tissue neoplasm
  44. Frey Syndrome
  45. Ganglioneuroma
  46. Gastrointestinal stromal tumor
  47. Genetic disease
  48. Genetic disorder
  49. Germ cell and embryonal cancer
  50. Germ cell cancer
  51. Glioblastoma
  52. Glioma
  53. Glioma of visual pathway
  54. Globe disease
  55. Gonadal disease
  56. Hemangioblastoma
  57. Hemangioma
  58. Hematologic cancer
  59. Hematopoietic system disease
  60. Hydrocephalus
  61. Hydrophthalmos
  62. Hypertension
  63. Infratentorial neoplasm
  64. Intellectual disability
  65. Intracranial arterial disease
  66. Intracranial hypertension
  67. Intracranial neoplasm
  68. Juvenile astrocytoma
  69. Juvenile myelomonocytic leukemia
  70. Juvenile pilocytic astrocytoma
  71. Learning disability
  72. LEOPARD syndrome
  73. Leukemia
  74. Li-Fraumeni syndrome
  75. Malignant glandular tumor of peripheral
  76. Malignant glioma
  77. Malignant intracranial neoplasm
  78. Malignant peripheral nerve sheath tumor
  79. Malignant triton tumor
  80. Medical disorder
  81. Meningioma
  82. Meningocele
  83. Mesenchymal cell neoplasm
  84. Monogenic disease
  85. Moyamoya disease
  86. Multiple endocrine neoplasia
  87. Multiple meningiomas
  88. Muscle cancer
  89. Myelodysplastic myeloproliferative cance
  90. Myeloid leukemia
  91. Neoplasm of autonomic nervous system
  92. Neoplasm of visual pathway
  93. Nerve sheath tumors
  94. Nervous system cancer
  95. Nervous system disease
  96. Neurilemmoma
  97. Neurilemmomatosis
  98. Neuroblastoma
  99. Neuroectodermal tumor
  100. Neuroendocrine tumor
  101. Neurofibroma
  102. Neurofibromatosis
  103. Neurofibrosarcoma
  104. Neuroma
  105. Neuropathy
  106. Noonan syndrome
  107. Obstructive hydrocephalus
  108. Optic nerve glioma
  109. Optic nerve neoplasm
  110. Orbit embryonal rhabdomyosarcoma
  111. Organ system cancer
  112. Peripheral nerve sheath neoplasm
  113. Peripheral nervous system neoplasm
  114. Piebaldism
  115. Pilocytic astrocytoma
  116. Pilocytic astrocytoma of childhood
  117. Pilomyxoid astrocytoma
  118. Pleomorphic xanthoastrocytoma
  119. Plexiform neurofibroma
  120. Plexiform schwannoma
  121. Precocious puberty
  122. Primary congenital glaucoma
  123. Progressive multifocal leukoencephalopat
  124. Pulmonary valve stenosis
  125. Pulsating exophthalmos
  126. Rhabdomyosarcoma
  127. Sarcoma
  128. Secondary hypertension
  129. Sensory system disease
  130. Skeletal muscle cancer
  131. Soft tissue cancer
  132. Somatostatinoma
  133. Specific developmental disease
  134. Spina bifida
  135. Subclavian artery aneurysm
  136. Tuberous sclerosis
  137. Tumor of meningothelial cell
  138. Uveal cancer
  139. Vascular disease
  140. Vascular tissue disease
  141. Von Hippel-Lindau disease

Stage Associations

This gene is associated with the following stages: