Gene Expression: PTGS2

Gene Data

  • Gene Symbol: PTGS2
  • Gene ID: 5743
  • Synonyms: COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
  • Description: prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Database Refs: HGNC:9605, MIM:600262, Ensembl:ENSG00000073756, HPRD:02599, Vega:OTTHUMG00000035473
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 1 out of 11 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters: No Clusters were found

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 210 diseases, scroll to view all:
  1. Actinic keratosis
  2. Active peptic ulcer disease
  3. Acute endometritis
  4. Adenocarcinoma
  5. Adenoma
  6. Alzheimer's disease
  7. Amyotrophic lateral sclerosis
  8. Angioedema
  9. Arterial occlusive disease
  10. Arteriopathy
  11. Arteriosclerosis
  12. Arteriosclerotic cardiovascular disease
  13. Arthritis
  14. Articular gout (disorder)
  15. Asthma
  16. Astrocytoma
  17. Atherosclerosis
  18. Atrophic gastritis
  19. Barrett's adenocarcinoma
  20. Basal ganglia disease
  21. Benign neoplasm
  22. Bile duct adenocarcinoma
  23. Bile duct cancer
  24. Bile duct carcinoma
  25. Bile reflux
  26. Biliary tract cancer
  27. Bladder carcinoma
  28. Bladder disease
  29. Bone disease
  30. Bone inflammation disease
  31. Brain cancer
  32. Brain disease
  33. Brain hypoxia-Ischemia
  34. Brain infarction
  35. Brain ischemia
  36. Brain neoplasm
  37. Breast cancer
  38. Breast carcinoma
  39. Breast carcinoma in situ
  40. Bronchial disease
  41. Cancer
  42. Carbohydrate metabolism disease
  43. Carcinoma
  44. Cardiovascular system disease
  45. Cell type cancer
  46. Central nervous system cancer
  47. Central nervous system disease
  48. Central nervous system neoplasm
  49. Cerebral artery occlusion
  50. Cerebrovascular accident
  51. Cerebrovascular disease
  52. Cervix neoplasm
  53. Cholangiocarcinoma
  54. Cognitive disease
  55. Colon adenocarcinoma
  56. Colon cancer
  57. Colon carcinoma
  58. Colonic neoplasm
  59. Colorectal cancer
  60. Cystitis
  61. Dementia
  62. Dermatitis
  63. Diabetes mellitus
  64. Diarrhea
  65. Disease
  66. Disease by infectious agent
  67. Disease of anatomical entity
  68. Disease of cellular proliferation
  69. Disease of mental health
  70. Disease of metabolism
  71. Ductal carcinoma in situ
  72. Dyspepsia
  73. Endocrine gland cancer
  74. Endocrine pancreas disease
  75. Endocrine system disease
  76. Endometrial adenocarcinoma
  77. Endometrial cancer
  78. Endometrial carcinoma
  79. Endometrial disease
  80. Endometriosis
  81. Endometritis
  82. Esophageal cancer
  83. Esophageal carcinoma
  84. Esophageal disease
  85. Esophagitis
  86. Esophagus adenocarcinoma
  87. Extrinsic cardiomyopathy
  88. Eye and adnexa disease
  89. Eye disease
  90. Familial adenomatous polyposis
  91. Female reproductive system disease
  92. Female reproductve organ cancer
  93. Functional gastric disease
  94. Gallbladder cancer
  95. Gallbladder carcinoma
  96. Gastric adenocarcinoma
  97. Gastritis
  98. Gastroesophageal reflux disease
  99. Gastrointestinal system cancer
  100. Gastrointestinal system disease
  101. Gastrointestinal system neoplasm
  102. Genetic disease
  103. Genitourinary cancer
  104. Glioma
  105. Globe disease
  106. Glucose metabolism disease
  107. Heart disease
  108. Heart failure
  109. Hematologic cancer
  110. Hepatobiliary disease
  111. Hepatocellular carcinoma
  112. Hypersensitivity reaction disease
  113. Hypertension
  114. Ileus
  115. Immune system disease
  116. In situ carcinoma
  117. Inflammatory bowel disease
  118. Integumentary system disease
  119. Intestinal cancer
  120. Intestinal disease
  121. Intestinal neoplasm
  122. Intestinal obstruction
  123. Intracranial neoplasm
  124. Ischemia
  125. Kidney disease
  126. Kidney failure
  127. Large intestine cancer
  128. Laryngeal carcinoma
  129. Larynx cancer
  130. Liver cancer
  131. Liver carcinoma
  132. Liver disease
  133. Lower respiratory tract disease
  134. Lung adenocarcinoma
  135. Lung cancer
  136. Lung carcinoma
  137. Lung disease
  138. Male reproductive organ cancer
  139. Malignant intracranial neoplasm
  140. Malignant ovarian surface epithelial-str
  141. Melanoma
  142. Mesenchymal cell neoplasm
  143. Monogenic disease
  144. Mouth disease
  145. Musculoskeletal system disease
  146. Myocardial infarction
  147. Myocardial ischemia
  148. Nasopharynx cancer
  149. Nasopharynx carcinoma
  150. Nervous system cancer
  151. Nervous system disease
  152. Neurodegenerative disease
  153. Neuropathy
  154. non-small cell lung carcinoma
  155. Nose disease
  156. Obstructive lung disease
  157. Oral cancer
  158. Organ system cancer
  159. Osteoarthritis
  160. Ovarian cancer
  161. Ovarian carcinoma
  162. Ovary epithelial cancer
  163. Pancreas adenocarcinoma
  164. Pancreas disease
  165. Pancreatic cancer
  166. Pancreatic carcinoma
  167. Pancreatitis
  168. Papilloma
  169. Parkinson's disease
  170. Peptic ulcer
  171. Periodontal disease
  172. Periodontitis
  173. Peripheral vascular disease
  174. Pleural disease
  175. Pleurisy
  176. pre-malignant neoplasm
  177. Prostate cancer
  178. Prostate carcinoma
  179. Reproductive organ cancer
  180. Reproductive system disease
  181. Respiratory system cancer
  182. Respiratory system disease
  183. Retinal disease
  184. Rheumatoid arthritis
  185. Sensory system disease
  186. Skin cancer
  187. Skin carcinoma
  188. Skin disease
  189. Soft tissue cancer
  190. Squamous cell carcinoma
  191. Stomach cancer
  192. Stomach carcinoma
  193. Stomach disease
  194. Synovitis
  195. Tauopathy
  196. Thoracic cancer
  197. Tooth disease
  198. Toxic encephalopathy
  199. Transitional cell carcinoma
  200. Ulcerative colitis
  201. Upper respiratory tract disease
  202. Urinary bladder cancer
  203. Urinary system disease
  204. Urinary tract cancer
  205. Urticaria
  206. Uterine cancer
  207. Uterine disease
  208. Uterine neoplasm
  209. Vascular disease
  210. Vascular skin disease

Stage Associations

This gene is associated with the following stages: No Stages were found