History:GENE:XRCC1    

Gene Expression: TOP1

Gene Data

  • Gene Symbol: TOP1
  • Gene ID: 7150
  • Synonyms: TOPI
  • Description: topoisomerase (DNA) I
  • Database Refs: HGNC:11986, MIM:126420, Ensembl:ENSG00000198900, HPRD:00535, Vega:OTTHUMG00000033057
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 0 out of 22 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 99 diseases, scroll to view all:
  1. Acute leukemia
  2. Adenocarcinoma
  3. Agranulocytosis
  4. Alopecia
  5. Anemia
  6. Astrocytoma
  7. Ataxia telangiectasia
  8. Axonal neuropathy
  9. Blood coagulation disease
  10. Blood platelet disease
  11. Brain cancer
  12. Brain neoplasm
  13. Breast cancer
  14. Breast carcinoma
  15. Cancer
  16. Carcinoma
  17. Cardiovascular system disease
  18. Cell type cancer
  19. Central nervous system cancer
  20. Central nervous system neoplasm
  21. Collagen disease
  22. Colon cancer
  23. Colon carcinoma
  24. Colorectal cancer
  25. Connective tissue disease
  26. Diarrhea
  27. Diffuse scleroderma
  28. Disease
  29. Disease by infectious agent
  30. Disease of anatomical entity
  31. Disease of cellular proliferation
  32. Female reproductve organ cancer
  33. Gastrointestinal system cancer
  34. Gastrointestinal system disease
  35. Genetic disease
  36. Genitourinary cancer
  37. Glioblastoma
  38. Glioma
  39. Hair disease
  40. Hematologic cancer
  41. Hematopoietic system disease
  42. Hemorrhagic disease
  43. Hypersensitivity reaction disease
  44. Hypersensitivity reaction type II diseas
  45. Hypotrichosis
  46. Immune system disease
  47. Integumentary system disease
  48. Interstitial lung disease
  49. Intestinal cancer
  50. Intracranial neoplasm
  51. Large intestine cancer
  52. Leukemia
  53. Leukocyte disease
  54. Leukopenia
  55. Limited scleroderma
  56. Lung cancer
  57. Lung carcinoma
  58. Lupus erythematosus
  59. Lymphoblastic leukemia
  60. Lymphoma
  61. Malignant glioma
  62. Malignant intracranial neoplasm
  63. Malignant ovarian surface epithelial-str
  64. Melanoma
  65. Mesenchymal cell neoplasm
  66. Monogenic disease
  67. Muscle cancer
  68. Musculoskeletal system disease
  69. Myeloid leukemia
  70. Neoplasm of autonomic nervous system
  71. Nervous system cancer
  72. Neuroblastoma
  73. Neutropenia
  74. non-small cell lung carcinoma
  75. Organ system cancer
  76. Ovarian cancer
  77. Ovarian carcinoma
  78. Ovary epithelial cancer
  79. Pancreatic cancer
  80. Peripheral nervous system neoplasm
  81. Pulmonary fibrosis
  82. Raynaud disease
  83. Reproductive organ cancer
  84. Respiratory system cancer
  85. Rhabdomyosarcoma
  86. Rheumatic disease
  87. Sarcoma
  88. Scleroderma
  89. Skeletal muscle cancer
  90. Soft tissue cancer
  91. Spinocerebellar ataxia
  92. Spinocerebellar degeneration
  93. Systemic lupus erythematosus
  94. Systemic scleroderma
  95. Thoracic cancer
  96. Thrombocytopenia
  97. Vaccinia
  98. Viral infectious disease
  99. Werner syndrome

Stage Associations

This gene is associated with the following stages: