Gene Expression: CASP3

Gene Data

  • Gene Symbol: CASP3
  • Gene ID: 836
  • Synonyms: CPP32, CPP32B, SCA-1
  • Description: caspase 3, apoptosis-related cysteine peptidase
  • Database Refs: HGNC:1504, MIM:600636, Ensembl:ENSG00000164305, HPRD:02799, Vega:OTTHUMG00000133681
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 1 out of 9 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 227 diseases, scroll to view all:
  1. Acute myeloid leukemia
  2. Acute myocardial infarction
  3. Acute pancreatitis
  4. Adenocarcinoma
  5. Adenoma
  6. Age related macular degeneration
  7. Alzheimer's disease
  8. Amyotrophic lateral sclerosis
  9. Anterior horn cell disease
  10. Arterial occlusive disease
  11. Arteriopathy
  12. Arteriosclerosis
  13. Arteriosclerotic cardiovascular disease
  14. Arthritis
  15. Astrocytoma
  16. Atherosclerosis
  17. B-cell lymphocytic neoplasm
  18. Bacterial infectious disease
  19. Basal ganglia disease
  20. Benign neoplasm
  21. Bile duct adenocarcinoma
  22. Bile duct cancer
  23. Bile duct carcinoma
  24. Biliary tract cancer
  25. Bone disease
  26. Bone inflammation disease
  27. Bone marrow cancer
  28. Bone marrow disease
  29. Bone tissue neoplasm
  30. Brain cancer
  31. Brain disease
  32. Brain edema
  33. Brain hypoxia-Ischemia
  34. Brain infarction
  35. Brain ischemia
  36. Brain neoplasm
  37. Breast cancer
  38. Breast carcinoma
  39. Burkitt's lymphoma
  40. Cancer
  41. Carbohydrate metabolism disease
  42. Carcinoma
  43. Cardiovascular system disease
  44. Carotid artery occlusion
  45. Cell type cancer
  46. Central nervous system cancer
  47. Central nervous system disease
  48. Central nervous system hereditary degene
  49. Central nervous system neoplasm
  50. Cerebral artery occlusion
  51. Cerebral infarction
  52. Cerebrovascular accident
  53. Cerebrovascular disease
  54. Cholangiocarcinoma
  55. Cholestasis
  56. Chronic leukemia
  57. Chronic lymphocytic leukemia
  58. Chronic myeloid leukemia
  59. Cognitive disease
  60. Colon adenocarcinoma
  61. Colon cancer
  62. Colon carcinoma
  63. Colorectal cancer
  64. Connective tissue neoplasm
  65. Degeneration of macula and posterior pol
  66. Dementia
  67. Demyelinating disease
  68. Diabetes mellitus
  69. Diabetic neuropathy
  70. Diabetic retinopathy
  71. Disease
  72. Disease by infectious agent
  73. Disease of anatomical entity
  74. Disease of cellular proliferation
  75. Disease of mental health
  76. Disease of metabolism
  77. Embryonal cancer
  78. Embryonal cancer of CNS
  79. Encephalitis
  80. Endocrine gland cancer
  81. Endocrine pancreas disease
  82. Endocrine system disease
  83. Esophageal cancer
  84. Extrinsic cardiomyopathy
  85. Eye and adnexa disease
  86. Eye disease
  87. Fatty liver
  88. Female reproductve organ cancer
  89. Fetal alcohol syndrome
  90. Gastrointestinal system cancer
  91. Gastrointestinal system disease
  92. Genetic disease
  93. Genitourinary cancer
  94. Germ cell and embryonal cancer
  95. Germ cell cancer
  96. Glaucoma
  97. Glioblastoma
  98. Glioma
  99. Globe disease
  100. Glucose metabolism disease
  101. Heart disease
  102. Heart failure
  103. Hematologic cancer
  104. Hematopoietic system disease
  105. Hepatitis
  106. Hepatobiliary disease
  107. Hepatoblastoma
  108. Hepatocellular carcinoma
  109. Huntington's disease
  110. Hyperglycemia
  111. Hypersensitivity reaction disease
  112. Hypersensitivity reaction type II diseas
  113. Hypertension
  114. Immune system disease
  115. Inborn errors of metabolism
  116. Infertility
  117. Inflammatory bowel disease
  118. Integumentary system disease
  119. Intestinal cancer
  120. Intestinal disease
  121. Intracranial neoplasm
  122. Ischemia
  123. Kidney cancer
  124. Kidney disease
  125. Kidney failure
  126. Large intestine cancer
  127. Leukemia
  128. Lipid metabolism disease
  129. Liver cancer
  130. Liver carcinoma
  131. Liver disease
  132. Lower respiratory tract disease
  133. Lung adenocarcinoma
  134. Lung cancer
  135. Lung carcinoma
  136. Lung disease
  137. Lymphoblastic leukemia
  138. Lymphoid leukemia
  139. Lymphoma
  140. Macular degeneration
  141. Male reproductive organ cancer
  142. Malignant glioma
  143. Malignant intracranial neoplasm
  144. Malignant ovarian surface epithelial-str
  145. Mature B-cell lymphocytic neoplasm
  146. Melanoma
  147. Mesenchymal cell neoplasm
  148. Monogenic disease
  149. Motor neuron disease
  150. Multiple myeloma
  151. Multiple sclerosis
  152. Muscle tissue disease
  153. Muscular atrophy
  154. Muscular disease
  155. Musculoskeletal system disease
  156. Myeloid leukemia
  157. Myeloma
  158. Myocardial infarction
  159. Myocardial ischemia
  160. Myopathy
  161. Nasopharynx cancer
  162. Nasopharynx carcinoma
  163. Neoplasm of autonomic nervous system
  164. Nervous system cancer
  165. Nervous system disease
  166. Neuroblastoma
  167. Neurodegenerative disease
  168. Neuroectodermal tumor
  169. Neuromuscular disease
  170. Neuropathy
  171. non-Hodgkin lymphoma
  172. non-small cell lung carcinoma
  173. Obstructive lung disease
  174. Occlusion precerebral artery
  175. Ocular cancer
  176. Oral cancer
  177. Organ system cancer
  178. Osteoarthritis
  179. Osteosarcoma
  180. Ovarian cancer
  181. Ovarian carcinoma
  182. Ovary epithelial cancer
  183. Pancreas disease
  184. Pancreatic cancer
  185. Pancreatic carcinoma
  186. Pancreatitis
  187. Parasitic infectious disease
  188. Parkinson's disease
  189. Perinatal necrotizing enterocolitis
  190. Peripheral nervous system neoplasm
  191. Primary bacterial infectious disease
  192. Primitive neuroectodermal tumor
  193. Prostate cancer
  194. Prostate carcinoma
  195. Reproductive organ cancer
  196. Reproductive system disease
  197. Respiratory system cancer
  198. Respiratory system disease
  199. Retinal cancer
  200. Retinal cell cancer
  201. Retinal degeneration
  202. Retinal disease
  203. Retinal ischemia
  204. Retinal vascular disease
  205. Retinoblastoma
  206. Rheumatoid arthritis
  207. Sarcoma
  208. Sensory system disease
  209. Skin cancer
  210. Skin disease
  211. Soft tissue cancer
  212. Spinal cord ischemia
  213. Spinal cord vascular disease
  214. Squamous cell carcinoma
  215. Stomach cancer
  216. T-cell leukemia
  217. Tauopathy
  218. Thoracic cancer
  219. Thyroid cancer
  220. Thyroid neoplasm
  221. Toxic encephalopathy
  222. Transient cerebral ischemia
  223. Urinary bladder cancer
  224. Urinary system disease
  225. Urinary tract cancer
  226. Vascular disease
  227. Viral infectious disease

Stage Associations

This gene is associated with the following stages: