History:CLUSTER:58    CLUSTER:37    CLUSTER:5    

Gene Expression: ALPL

Gene Data

  • Gene Symbol: ALPL
  • Gene ID: 249
  • Synonyms: AP-TNAP, APTNAP, HOPS, TNAP, TNSALP
  • Description: alkaline phosphatase, liver/bone/kidney
  • Database Refs: HGNC:438, MIM:171760, Ensembl:ENSG00000162551, HPRD:01377, Vega:OTTHUMG00000002949
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 0 out of 14 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 394 diseases, scroll to view all:
  1. Abdominal tuberculosis
  2. Acalculous cholecystitis
  3. Acquired immunodeficiency syndrome
  4. Acrodermatitis enteropathica
  5. Acute cholangitis
  6. Acute leukemia
  7. Acute pancreatitis
  8. Adenocarcinoma
  9. Adenoma
  10. Adrenal gland disease
  11. Agranulocytosis
  12. Alcohol abuse
  13. Alcoholic liver cirrhosis
  14. Alopecia
  15. Amenorrhea
  16. Amyloidosis
  17. Anemia
  18. Ankylosing spondylitis
  19. Ankylosis
  20. Arterial occlusive disease
  21. Arteriopathy
  22. Arteriosclerosis
  23. Arteriosclerotic cardiovascular disease
  24. Arthritis
  25. Arthropathy
  26. Articular cartilage disease
  27. Ascending cholangitis
  28. Asthma
  29. Atherosclerosis
  30. Autoimmune disease of endocrine system
  31. Autoimmune disease of gastrointestinal t
  32. Autoimmune disease of urogenital tract
  33. Autoimmune hepatitis
  34. B-cell lymphocytic neoplasm
  35. Babesiosis
  36. Bacterial infectious disease
  37. Benign neoplasm
  38. Bile duct adenocarcinoma
  39. Bile duct cancer
  40. Bile duct carcinoma
  41. Bile duct disease
  42. Biliary atresia
  43. Biliary tract cancer
  44. Biliary tract disease
  45. Blood coagulation disease
  46. Blood platelet disease
  47. Blood protein disease
  48. Bone cancer
  49. Bone development disease
  50. Bone disease
  51. Bone inflammation disease
  52. Bone marrow cancer
  53. Bone marrow disease
  54. Bone remodeling disease
  55. Bone resorption disease
  56. Bone tissue neoplasm
  57. Bowel dysfunction
  58. Brain disease
  59. Breast adenocarcinoma
  60. Breast cancer
  61. Breast carcinoma
  62. Bronchial disease
  63. Bronchopneumonia
  64. Calcinosis
  65. Calciphylaxis
  66. Calcium metabolism disease
  67. Camurati-Engelmann disease
  68. Cancer
  69. Candidiasis
  70. Carbohydrate metabolism disease
  71. Carcinoma
  72. Cardiovascular system disease
  73. Cartilage disease
  74. Celiac disease
  75. Cell type cancer
  76. Central nervous system disease
  77. Central nervous system neoplasm
  78. Central nervous system vasculitis
  79. Cholangiocarcinoma
  80. Cholangitis
  81. Cholecystitis
  82. Choledochal cyst
  83. Choledocholithiasis
  84. Cholelithiasis
  85. Cholestasis
  86. Chondrosarcoma
  87. Choriocarcinoma
  88. Chromosomal disease
  89. Chronic kidney failure
  90. Chronic myeloid leukemia
  91. Cleidocranial dysplasia
  92. Collagen disease
  93. Colon cancer
  94. Colon carcinoma
  95. Colonic disease
  96. Colorectal cancer
  97. Common bile duct disease
  98. Connective tissue disease
  99. Connective tissue neoplasm
  100. Constipation
  101. Craniosynostosis
  102. Crohn's disease
  103. Cystic fibrosis
  104. Dermatitis
  105. Diabetes mellitus
  106. Diarrhea
  107. Disease
  108. Disease by infectious agent
  109. Disease of anatomical entity
  110. Disease of cellular proliferation
  111. Disease of mental health
  112. Disease of metabolism
  113. Down syndrome
  114. drug-induced hepatitis
  115. Duodenal disease
  116. Duodenal obstruction
  117. Dysgerminoma
  118. Dysostosis
  119. Echinococcosis
  120. Embryonal cancer
  121. Embryonal carcinoma
  122. End stage renal failure
  123. Endocrine gland cancer
  124. Endocrine pancreas disease
  125. Endocrine system disease
  126. Eosinophilia
  127. Esophageal varix
  128. Extragonadal germ cell cancer
  129. Extragonadal germ cell malignant tumor
  130. Extrahepatic cholestasis
  131. Extrapulmonary tuberculosis
  132. Eye and adnexa disease
  133. Eye disease
  134. Familial hypophosphatemia
  135. Fascioliasis
  136. Fatty liver
  137. Female reproductive system disease
  138. Female reproductve organ cancer
  139. Fibrogenesis imperfecta ossium
  140. Fibrous dysplasia
  141. Fungal infectious disease
  142. Gallbladder disease
  143. Gastroenteritis
  144. Gastrointestinal system cancer
  145. Gastrointestinal system disease
  146. Gastrointestinal tuberculosis
  147. Genetic disease
  148. Genitourinary cancer
  149. Germ cell and embryonal cancer
  150. Germ cell cancer
  151. Germ cell tumor of central nervous syste
  152. Germinoma
  153. Giant cell tumor
  154. Gingival disease
  155. Gingivitis
  156. Globe disease
  157. Glucose metabolism disease
  158. Gnathomiasis
  159. Goiter
  160. Gonadal disease
  161. Granulomatous hepatitis
  162. Graves' disease
  163. Hair disease
  164. Heart disease
  165. Heart valve disease
  166. Hematologic cancer
  167. Hematopoietic system disease
  168. Hemolytic anemia
  169. Hemorrhagic disease
  170. Hepatic encephalopathy
  171. Hepatic tuberculosis
  172. Hepatic vascular disease
  173. Hepatitis
  174. Hepatitis A
  175. Hepatitis B
  176. Hepatitis C
  177. Hepatobiliary disease
  178. Hepatocellular carcinoma
  179. Hereditary hyperbilirubinemia
  180. Hereditary hypophosphatemic rickets
  181. Histoplasmosis
  182. Human immunodeficiency virus infectious
  183. Hypercalcemia
  184. Hypercholesterolemia
  185. Hyperglycemia
  186. Hyperostosis
  187. Hyperparathyroidism
  188. Hyperphosphatemia
  189. Hypersensitivity reaction disease
  190. Hypersensitivity reaction type II diseas
  191. Hypersensitivity reaction type IV diseas
  192. Hypertension
  193. Hyperthyroidism
  194. Hypoparathyroidism
  195. Hypophosphatasia
  196. Hypophosphatemia
  197. Hypothyroidism
  198. Hypotrichosis
  199. Immune system disease
  200. Impaired renal function disease
  201. Inborn errors carbohydrate metabolism
  202. Inborn errors metal metabolism
  203. Inborn errors of metabolism
  204. Inborn errors renal tubular transport
  205. Infectious mononucleosis
  206. Inflammatory bowel disease
  207. Integumentary system disease
  208. Interstitial nephritis
  209. Intestinal cancer
  210. Intestinal disease
  211. Intestinal obstruction
  212. Intracranial germinoma
  213. Intracranial neoplasm
  214. Intrahepatic cholestasis
  215. Ischemia
  216. Ischemic bone disease
  217. Kidney cancer
  218. Kidney disease
  219. Kidney failure
  220. Large intestine cancer
  221. Leprosy
  222. Leukemia
  223. Leukemoid reaction
  224. Leukocyte disease
  225. Leukopenia
  226. Lipid metabolism disease
  227. Liver cancer
  228. Liver carcinoma
  229. Liver cirrhosis
  230. Liver disease
  231. Lower respiratory tract disease
  232. Lung cancer
  233. Lung carcinoma
  234. Lung disease
  235. Lymphatic system disease
  236. Lymphoblastic leukemia
  237. Lymphoid leukemia
  238. Lymphoma
  239. Lymphopenia
  240. Lymphoproliferative disease
  241. Malaria
  242. Male reproductive organ cancer
  243. Male reproductive system disease
  244. Malignant intracranial germ cell neoplas
  245. Malignant intracranial neoplasm By Morph
  246. Malignant ovarian surface epithelial-str
  247. Mammary Paget's disease
  248. McCune Albright Syndrome
  249. Medical disorder
  250. Melanoma
  251. Mesenchymal cell neoplasm
  252. Mineral metabolism disease
  253. Monogenic disease
  254. Mouth disease
  255. Multiple myeloma
  256. Muscle tissue disease
  257. Muscular disease
  258. Musculoskeletal system disease
  259. Myelofibrosis
  260. Myeloid leukemia
  261. Myeloma
  262. Myelophthisic anemia
  263. Myopathy
  264. Myositis
  265. Nephritis
  266. Nephrocalcinosis
  267. Nephrolithiasis
  268. Nephrosis
  269. Nephrotic syndrome
  270. Nervous system cancer
  271. Nervous system disease
  272. Neurodegenerative disease
  273. Neuropathy
  274. Neutropenia
  275. Nontoxic goiter
  276. Normocytic anemia
  277. Nutrition disease
  278. Nutritional deficiency disease
  279. Obstructive jaundice
  280. Obstructive lung disease
  281. Ollier disease
  282. Opportunistic mycosis
  283. Organ system cancer
  284. Osteitis fibrosa
  285. Osteoarthritis
  286. Osteochondrodysplasia
  287. Osteogenesis imperfecta
  288. Osteomalacia
  289. Osteomyelitis
  290. Osteonecrosis
  291. Osteopetrosis
  292. Osteoporosis
  293. Osteosarcoma
  294. Osteosclerosis
  295. Ovarian cancer
  296. Ovarian carcinoma
  297. Ovary epithelial cancer
  298. Overnutrition
  299. Paget's disease of bone
  300. Pancreas disease
  301. Pancreatic cancer
  302. Pancreatitis
  303. Pancytopenia
  304. Parasitic helminthiasis infectious disea
  305. Parasitic infectious disease
  306. Parasitic protozoa infectious disease
  307. Parathyroid adenoma
  308. Parathyroid carcinoma
  309. Parathyroid gland cancer
  310. Parathyroid gland disease
  311. Parathyroid neoplasm
  312. Peptic ulcer
  313. Pericholangitis
  314. Periodontal disease
  315. Periodontitis
  316. Peritonitis
  317. Phlebitis
  318. Phosphorus metabolism disease
  319. Physical disorder
  320. Placenta neoplasm
  321. Pneumonia
  322. Polycythemia
  323. Polycythemia vera
  324. Polymyalgia rheumatica
  325. Portal hypertension
  326. Portal vein thrombosis
  327. pre-eclampsia
  328. Primary bacterial infectious disease
  329. Primary biliary cirrhosis
  330. Primary hyperoxaluria
  331. Primary hyperparathyroidism
  332. Primary systemic mycosis
  333. Prostate cancer
  334. Prostate carcinoma
  335. Proteinuria
  336. Pseudogout
  337. Pyelitis
  338. Pyelonephritis
  339. Renal carcinoma
  340. Renal cell carcinoma
  341. Renal osteodystrophy
  342. Renal tubular acidosis
  343. Reproductive organ cancer
  344. Reproductive system disease
  345. Respiratory failure
  346. Respiratory system cancer
  347. Respiratory system disease
  348. Rheumatoid arthritis
  349. Rickets
  350. Root resorption
  351. Sarcoidosis
  352. Sarcoma
  353. Schistosomiasis
  354. Sclerosing cholangitis
  355. Scurvy
  356. Secondary hyperparathyroidism
  357. Seminoma
  358. Sensory system disease
  359. Skin disease
  360. Soft tissue cancer
  361. Spermatocytoma
  362. Substance abuse
  363. substance-related disease
  364. Synostosis
  365. Syphilis
  366. Systemic mycosis
  367. Teeth hard tissue disease
  368. Temporal arteritis
  369. Teratoma
  370. Testicular germ cell cancer
  371. Testicular malignant germ cell cancer
  372. Testicular neoplasm
  373. Testis seminoma
  374. Thoracic cancer
  375. Thrombocytopenia
  376. Thrombocytosis
  377. Thyroid gland disease
  378. Thyrotoxicosis
  379. Tooth disease
  380. Tooth resorption
  381. Tuberculosis
  382. Ulcerative colitis
  383. Uremia
  384. Urinary system disease
  385. Urinary tract cancer
  386. Vascular disease
  387. Vasculitis
  388. Vein disease
  389. Vericose veins
  390. Viral hepatitis
  391. Viral infectious disease
  392. Vitamin K deficiency hemorrhagic disease
  393. Wilson disease
  394. Worth's syndrome

Stage Associations

This gene is associated with the following stages: