Gene Expression: POMC

Gene Data

  • Gene Symbol: POMC
  • Gene ID: 5443
  • Synonyms: ACTH, CLIP, LPH, MSH, NPP, POC
  • Description: proopiomelanocortin
  • Database Refs: HGNC:9201, MIM:176830, Ensembl:ENSG00000115138, HPRD:01462, Vega:OTTHUMG00000094764
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 0 out of 5 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 350 diseases, scroll to view all:
  1. Achalasia
  2. Acromegaly
  3. ACTH-producing pituitary tumor
  4. ACTH-secreting pituitary adenoma
  5. Acute thyroiditis
  6. Addison's disease
  7. Adenocarcinoma
  8. Adenoma
  9. Adrenal adenoma
  10. Adrenal cancer
  11. Adrenal carcinoma
  12. Adrenal cortex disease
  13. Adrenal cortical hypofunction
  14. Adrenal gland cancer
  15. Adrenal gland disease
  16. Adrenal gland hyperfunction
  17. Adrenal hyperplasia
  18. Adrenal rest tumor
  19. Adrenocortical carcinoma
  20. Adrenocortical hyperplasia
  21. Adrenoleukodystrophy
  22. Alcohol abuse
  23. Alopecia
  24. Amenorrhea
  25. Amnestic disease
  26. Anemia
  27. Anovulation
  28. Anxiety disease
  29. Arachnoiditis
  30. Arthritis
  31. Articular gout (disorder)
  32. Asthma
  33. Atopic dermatitis
  34. Autoimmune disease of endocrine system
  35. Autoimmune disease of the nervous system
  36. Autoimmune polyendocrine syndrome type 2
  37. Autoimmune thyroiditis
  38. Bacterial infectious disease
  39. Basophil adenoma
  40. Benign neoplasm
  41. Bone disease
  42. Bone inflammation disease
  43. Bone remodeling disease
  44. Bone resorption disease
  45. Brain cancer
  46. Brain disease
  47. Brain neoplasm
  48. Breast cancer
  49. Breast disease
  50. Bronchial disease
  51. Bronchogenic carcinoma
  52. Bronchus adenoma
  53. Bronchus cancer
  54. Calcium metabolism disease
  55. Cancer
  56. Carbohydrate metabolism disease
  57. Carcinoid syndrome
  58. Carcinoma
  59. Cardiovascular system disease
  60. Carney complex
  61. Cell type cancer
  62. Central nervous system cancer
  63. Central nervous system disease
  64. Central nervous system neoplasm
  65. Cerebral degeneration
  66. Cerebrovascular accident
  67. Cerebrovascular disease
  68. Cholera
  69. Chromophobe adenoma
  70. Chromosomal disease
  71. Chronic fatigue syndrome
  72. Cocaine abuse
  73. Cocaine dependence
  74. Cognitive disease
  75. Common migraine
  76. Congenital adrenal hyperplasia
  77. Congenital adrenal insufficiency
  78. Congestive heart failure
  79. Conn syndrome
  80. Connective tissue disease
  81. Cranial nerve disease
  82. Craniopharyngioma
  83. Cushing syndrome
  84. Delayed puberty
  85. Demyelinating disease
  86. Dermatitis
  87. Dermatomyositis
  88. Developmental disease of mental health
  89. Diabetes insipidus
  90. Diabetes mellitus
  91. Diarrhea
  92. Disease
  93. Disease by infectious agent
  94. Disease of anatomical entity
  95. Disease of cellular proliferation
  96. Disease of mental health
  97. Disease of metabolism
  98. Drug dependence
  99. Empty sella syndrome
  100. Encephalitis
  101. Endocrine gland cancer
  102. Endocrine pancreas cancer
  103. Endocrine pancreas disease
  104. Endocrine syndrome
  105. Endocrine system disease
  106. Endogenous depression
  107. Eosinophilia
  108. Epilepsy
  109. Esophageal disease
  110. Essential hypertension
  111. Exophthalmic ophthalmoplegia
  112. Extrapulmonary tuberculosis
  113. Extrinsic cardiomyopathy
  114. Eye and adnexa disease
  115. Eye disease
  116. Female reproductive system disease
  117. Fibromyalgia
  118. Follicular thyroid carcinoma
  119. Functioning pituitary adenoma
  120. Fungal infectious disease
  121. Gastrointestinal system disease
  122. Generalized epilepsy
  123. Genetic disease
  124. Genitourinary cancer
  125. Germ cell and embryonal cancer
  126. Germ cell cancer
  127. Globe disease
  128. Glomerulonephritis
  129. glucocorticoid-remediable aldosteronism
  130. Glucose intolerance
  131. Glucose metabolism disease
  132. Goiter
  133. Gonadal disease
  134. Gynecomastia
  135. Hair disease
  136. Heart disease
  137. Heart failure
  138. Hematologic cancer
  139. Hematopoietic system disease
  140. Hepatitis
  141. Hepatobiliary disease
  142. Heroin dependence
  143. Hormone producing pituitary neoplasm
  144. Human immunodeficiency virus infectious
  145. Hyperaldosteronism
  146. Hyperandrogenism
  147. Hypercalcemia
  148. Hyperglycemia
  149. Hyperinsulinism
  150. Hyperpituitarism
  151. Hyperprolactinemia
  152. Hypersensitivity reaction disease
  153. Hypersensitivity reaction type I disease
  154. Hypersensitivity reaction type II diseas
  155. Hypertension
  156. Hyperthyroidism
  157. Hypertrichosis
  158. Hypertrophy of breast
  159. Hypoglycemia
  160. Hypogonadism
  161. Hypokalemia
  162. Hypopituitarism
  163. Hypothalamic disease
  164. Hypothyroidism
  165. Hypotrichosis
  166. Immune system cancer
  167. Immune system disease
  168. Impotence
  169. Inappropriate ADH syndrome
  170. Inborn errors of metabolism
  171. Inborn errors steroid metabolism
  172. Infantile epileptic encephalopathy
  173. Infertility
  174. Inflammatory bowel disease
  175. Integumentary system disease
  176. Intellectual disability
  177. Intestinal disease
  178. Intracranial hypertension
  179. Intracranial neoplasm
  180. Irritable bowel syndrome
  181. Ischemia
  182. Islet cell tumor
  183. Kidney disease
  184. Kidney failure
  185. Klinefelter's syndrome
  186. Landau-Kleffner syndrome
  187. Lennox-Gastaut syndrome
  188. Leukocyte disease
  189. Leukodystrophy
  190. Leukopenia
  191. Leydig cell tumor
  192. Lipoid nephrosis
  193. Liver disease
  194. Lower respiratory tract disease
  195. Lung cancer
  196. Lung carcinoma
  197. Lung disease
  198. Lung oat cell carcinoma
  199. Lung small cell carcinoma
  200. Lupus erythematosus
  201. Male reproductive system disease
  202. Malignant intracranial neoplasm
  203. McCune Albright Syndrome
  204. Mediastinal lipomatosis
  205. Medical disorder
  206. Melancholia
  207. Melanoma
  208. Meningitis
  209. Mental depression
  210. Migraine
  211. Mineral metabolism disease
  212. Monogenic disease
  213. Mood disease
  214. Morbid obesity
  215. Motion sickness
  216. Multiple endocrine neoplasia
  217. Multiple sclerosis
  218. Muscle tissue disease
  219. Muscular disease
  220. Musculoskeletal system disease
  221. Myasthenia gravis
  222. Myocardial infarction
  223. Myocardial ischemia
  224. Myopathy
  225. Myositis
  226. Nasal cavity disease
  227. Necrosis of pituitary
  228. Nelson syndrome
  229. Neonatal abstinence syndrome
  230. Neoplasm of autonomic nervous system
  231. Neoplasm of sella turcica
  232. Nephritis
  233. Nephrosis
  234. Nephrotic syndrome
  235. Nervous system cancer
  236. Nervous system disease
  237. Neuroblastoma
  238. Neurodegenerative disease
  239. Neuroectodermal tumor
  240. Neuroendocrine carcinoma
  241. Neuroendocrine tumor
  242. Neurohypophyseal diabetes insipidus
  243. Neuromuscular disease
  244. Neuromuscular junction disease
  245. Neuropathy
  246. Nodular nonsuppurative panniculitis
  247. Nose disease
  248. Nutrition disease
  249. Obesity
  250. Obstructive lung disease
  251. Opiate addiction
  252. Organ system cancer
  253. Osteoporosis
  254. Ovarian disease
  255. Overnutrition
  256. Pancreas disease
  257. Pancreatic cancer
  258. Pancreatic endocrine carcinoma
  259. Panhypopituitarism
  260. Parathyroid gland disease
  261. Partial epilepsy
  262. Penile disease
  263. Peptic ulcer
  264. Peripheral nervous system disease
  265. Peripheral nervous system neoplasm
  266. Persistent fetal circulation syndrome
  267. Pervasive developmental disease
  268. Physical disorder
  269. Pituitary adenoma
  270. Pituitary apoplexy
  271. Pituitary carcinoma
  272. Pituitary disease
  273. Pituitary gland cancer
  274. Pituitary infarct
  275. Pituitary neoplasm
  276. pituitary-dependent Cushing's disease
  277. Pneumonia
  278. Polycystic ovary syndrome
  279. post-vaccinal encephalitis
  280. Precocious puberty
  281. Premenstrual tension
  282. Primary bacterial infectious disease
  283. Primary systemic mycosis
  284. Prolactin producing pituitary tumor
  285. Prolactinoma
  286. Pseudohermaphroditism
  287. Psychogenic depressive psychosis
  288. Psychotic disease
  289. Pulmonary hypertension
  290. Pulmonary tuberculosis
  291. Renal glycosuria
  292. Reproductive organ neoplasm
  293. Reproductive system disease
  294. Respiratory failure
  295. Respiratory system cancer
  296. Respiratory system disease
  297. Retrograde amnesia
  298. Rheumatic chorea
  299. Rheumatic fever
  300. Rheumatic heart disease
  301. Rheumatic pericarditis
  302. Rheumatoid arthritis
  303. Rhinitis
  304. Schizophrenia
  305. Scurvy
  306. Sensory system disease
  307. Sex cord-stromal neoplasm
  308. Sex differentiation disease
  309. Sexual disease
  310. Sexual dysfunction
  311. Sheehan syndrome
  312. Shwartzman phenomenon
  313. Skin cancer
  314. Skin disease
  315. Skull base neoplasm
  316. Small cell carcinoma
  317. Specific developmental disease
  318. Status asthmaticus
  319. Substance abuse
  320. Substance dependence
  321. substance-related disease
  322. Supratentorial cancer
  323. Supratentorial neoplasm
  324. Syndrome
  325. Systemic lupus erythematosus
  326. Systemic mycosis
  327. Thoracic cancer
  328. Thymic carcinoma
  329. Thymus cancer
  330. Thyroid cancer
  331. Thyroid carcinoma
  332. Thyroid gland disease
  333. Thyroid medullary carcinoma
  334. Thyroid neoplasm
  335. Thyroiditis
  336. Thyrotoxicosis
  337. Trichinosis
  338. Trigeminal nerve disease
  339. Trigeminal neuralgia
  340. triple-A syndrome
  341. Tuberculosis
  342. Tuberous sclerosis
  343. Tumors of adrenal cortex
  344. Typhoid fever
  345. Ulcerative colitis
  346. Upper respiratory tract disease
  347. Urinary system disease
  348. Vascular disease
  349. Viral infectious disease
  350. Withdrawal disease

Stage Associations

This gene is associated with the following stages: