History:GENE:IL5    GENE:IL3    GENE:IL1B    GENE:IGFBP6    GENE:ICAM1    

Gene Expression: IL6

Gene Data

  • Gene Symbol: IL6
  • Gene ID: 3569
  • Synonyms: BSF2, HGF, HSF, IFNB2, IL-6
  • Description: interleukin 6 (interferon, beta 2)
  • Database Refs: HGNC:6018, MIM:147620, Ensembl:ENSG00000136244, HPRD:00970, Vega:OTTHUMG00000023178
  • Links: Allen Brain Atlas,NCBI, GeneCards
Splicing Dynamics: DEXseq identifies changes in 0 out of 7 exons in this gene. (More about DEXSeq here)

Cluster Associations

This gene is associated with the following clusters:

Disease Associations

This gene is associated with the following diseases. Clicking on the disease will take you to the disease association entry for that disease.

This gene is associated with 484 diseases, scroll to view all:
  1. Abdominal aortic aneurysm
  2. Acquired immunodeficiency syndrome
  3. Acute myeloid leukemia
  4. Acute myocardial infarction
  5. Acute pancreatitis
  6. Acute pyelonephritis
  7. Adenocarcinoma
  8. Adenoma
  9. Adult respiratory distress syndrome
  10. Adult T-cell leukemia
  11. adult-onset Still's disease
  12. Agammaglobulinemia
  13. Aggressive periodontitis
  14. Agranulocytosis
  15. Alcoholic hepatitis
  16. Alcoholic liver cirrhosis
  17. Allergic asthma
  18. Allergic conjunctivitis
  19. Allergic rhinitis
  20. Alzheimer's disease
  21. Amyloidosis
  22. Anemia
  23. Aneurysm
  24. Ankylosing spondylitis
  25. Aortic aneurysm
  26. Aortic disease
  27. Aplastic anemia
  28. Appendicitis
  29. Arterial occlusive disease
  30. Arteriopathy
  31. Arteriosclerosis
  32. Arteriosclerotic cardiovascular disease
  33. Arthritis
  34. Arthropathy
  35. Aseptic meningitis
  36. Asthma
  37. Astrocytoma
  38. Atherosclerosis
  39. Atopic dermatitis
  40. Auditory system disease
  41. Autoimmune disease of blood
  42. Autoimmune disease of cardiovascular sys
  43. Autoimmune disease of endocrine system
  44. Autoimmune disease of gastrointestinal t
  45. Autoimmune disease of the nervous system
  46. Autoimmune disease of urogenital tract
  47. Autoimmune thyroiditis
  48. B cell deficiency
  49. B-cell lymphocytic neoplasm
  50. Bacterial infectious disease
  51. Bacterial meningitis
  52. Bacterial pneumonia
  53. Bacterial vaginosis
  54. Bacteriuria
  55. Basal ganglia disease
  56. Behcet's disease
  57. Benign neoplasm
  58. Bile duct adenocarcinoma
  59. Bile duct cancer
  60. Bile duct carcinoma
  61. Bile duct disease
  62. Biliary tract cancer
  63. Biliary tract disease
  64. Bladder disease
  65. Blood coagulation disease
  66. Blood platelet disease
  67. Blood protein disease
  68. Bone disease
  69. Bone inflammation disease
  70. Bone marrow cancer
  71. Bone marrow disease
  72. Bone remodeling disease
  73. Bone resorption disease
  74. Brain cancer
  75. Brain disease
  76. Brain edema
  77. Brain hypoxia-Ischemia
  78. Brain infarction
  79. Brain ischemia
  80. Brain neoplasm
  81. Breast adenocarcinoma
  82. Breast cancer
  83. Breast carcinoma
  84. Bronchial disease
  85. Bronchiolitis
  86. Bronchiolitis obliterans
  87. Bronchitis
  88. Bronchopulmonary dysplasia
  89. Burning mouth syndrome
  90. Calcium metabolism disease
  91. Cancer
  92. Candidiasis
  93. Carbohydrate metabolism disease
  94. Carcinoma
  95. Cardiovascular cancer
  96. Cardiovascular system disease
  97. Cecal disease
  98. Celiac disease
  99. Cell type cancer
  100. Central nervous system cancer
  101. Central nervous system disease
  102. Central nervous system neoplasm
  103. Central nervous system vasculitis
  104. Central retinal vein occlusion
  105. Cerebral artery occlusion
  106. Cerebral infarction
  107. Cerebral malaria
  108. Cerebral palsy
  109. Cerebrovascular accident
  110. Cerebrovascular disease
  111. Chagas disease
  112. Cholangiocarcinoma
  113. Cholangitis
  114. Cholera
  115. Cholestasis
  116. Chronic conjunctivitis
  117. Chronic fatigue syndrome
  118. Chronic interstitial cystitis
  119. Chronic kidney failure
  120. Chronic leukemia
  121. Chronic lymphocytic leukemia
  122. Chronic obstructive pulmonary disease
  123. Coccidiosis
  124. Cognitive disease
  125. Collagen disease
  126. Colon cancer
  127. Colorectal cancer
  128. Combined T cell and B cell immunodeficie
  129. Commensal bacterial infectious disease
  130. Common cold
  131. Compartment syndrome
  132. Complex regional pain syndrome
  133. Congenital heart defect
  134. Congestive heart failure
  135. Conjunctival disease
  136. Conjunctivitis
  137. Connective tissue disease
  138. Connective tissue neoplasm
  139. Contact dermatitis
  140. Corneal disease
  141. Coronary heart disease
  142. Crohn's disease
  143. Cystic fibrosis
  144. Cysticercosis
  145. Cystitis
  146. Dementia
  147. Demyelinating disease
  148. Dengue disease
  149. Dengue hemorrhagic fever
  150. Dengue shock syndrome
  151. Dermatitis
  152. Diabetes mellitus
  153. Diabetic retinopathy
  154. Diarrhea
  155. Dilated cardiomyopathy
  156. Diphtheria
  157. Disease
  158. Disease by infectious agent
  159. Disease of anatomical entity
  160. Disease of cellular proliferation
  161. Disease of mental health
  162. Disease of metabolism
  163. Disseminated intravascular coagulation
  164. Encephalitis
  165. Encephalomalacia
  166. Encephalomyelitis
  167. End stage renal failure
  168. Endocarditis
  169. Endocrine gland cancer
  170. Endocrine pancreas disease
  171. Endocrine system disease
  172. Endometriosis
  173. Eosinophilia
  174. Esophageal cancer
  175. Euthyroid sick syndrome
  176. Extrinsic allergic alveolitis
  177. Extrinsic cardiomyopathy
  178. Eye and adnexa disease
  179. Eye disease
  180. Eye lymphoma
  181. Familial Mediterranean fever
  182. Fatty liver
  183. Female reproductive system disease
  184. Female reproductve organ cancer
  185. Fibromyalgia
  186. Filariasis
  187. Fungal infectious disease
  188. Gastritis
  189. Gastroenteritis
  190. Gastrointestinal system cancer
  191. Gastrointestinal system disease
  192. Genetic disease
  193. Genitourinary cancer
  194. Gingival disease
  195. Gingivitis
  196. Glioblastoma
  197. Glioma
  198. Globe disease
  199. Glomerulonephritis
  200. Glucose intolerance
  201. Glucose metabolism disease
  202. Goiter
  203. Graves' disease
  204. Heart disease
  205. Heart failure
  206. Heart valve disease
  207. Hematologic cancer
  208. Hematopoietic system disease
  209. Hemolytic anemia
  210. Hemophagocytic lymphohistiocytosis
  211. Hemorrhagic disease
  212. Hemorrhagic fever with renal syndrome
  213. Hepatic encephalopathy
  214. Hepatitis
  215. Hepatitis B
  216. Hepatitis C
  217. Hepatobiliary disease
  218. Hepatocellular carcinoma
  219. Herpes simplex
  220. Human immunodeficiency virus infectious
  221. Hypercalcemia
  222. Hypercholesterolemia
  223. Hypergammaglobulinemia
  224. Hyperglycemia
  225. Hyperinsulinism
  226. Hypersensitivity reaction disease
  227. Hypersensitivity reaction type I disease
  228. Hypersensitivity reaction type II diseas
  229. Hypersensitivity reaction type IV diseas
  230. Hypertension
  231. Hyperthyroidism
  232. Ideopathic interstitial pneumonia
  233. Idiopathic pulmonary fibrosis
  234. IgA glomerulonephritis
  235. Ileus
  236. Immune system disease
  237. Inborn errors of metabolism
  238. Infertility
  239. Inflammatory bowel disease
  240. Influenza
  241. Integumentary system disease
  242. Intermediate coronary syndrome
  243. Interstitial cystitis
  244. Interstitial lung disease
  245. Intestinal cancer
  246. Intestinal disease
  247. Intestinal obstruction
  248. Intracranial neoplasm
  249. Intraocular lymphoma
  250. Intrinsic cardiomyopathy
  251. Ischemia
  252. Juvenile rheumatoid arthritis
  253. Kaposi's sarcoma
  254. Kawasaki disease
  255. Keratitis
  256. Kidney cancer
  257. Kidney disease
  258. Kidney failure
  259. Large intestine cancer
  260. Leishmaniasis
  261. Leprosy
  262. Leukemia
  263. Leukocyte disease
  264. Leukopenia
  265. Lichen disease
  266. Lichen planus
  267. Lipid metabolism disease
  268. Lipodystrophy
  269. Listeriosis
  270. Liver cancer
  271. Liver carcinoma
  272. Liver cirrhosis
  273. Liver disease
  274. Lower respiratory tract disease
  275. Lung cancer
  276. Lung carcinoma
  277. Lung disease
  278. Lupus erythematosus
  279. Lyme disease
  280. Lymph node disease
  281. Lymphadenitis
  282. Lymphatic system disease
  283. Lymphoblastic leukemia
  284. Lymphoid leukemia
  285. Lymphoma
  286. Lymphopenia
  287. Lymphoproliferative disease
  288. Macroglobulinemia
  289. Macular retinal edema
  290. Malaria
  291. Male reproductive organ cancer
  292. Male reproductive system disease
  293. Malignant intracranial neoplasm
  294. Malignant vascular tumor
  295. Mammary Paget's disease
  296. Mastitis
  297. Mature B-cell lymphocytic neoplasm
  298. Melanoma
  299. Meningitis
  300. Meningoencephalitis
  301. Mesangial proliferative glomerulonephrit
  302. Mesenchymal cell neoplasm
  303. Microcytic anemia
  304. Middle ear disease
  305. Mineral metabolism disease
  306. Monoclonal gammopathy of uncertain signi
  307. Monogenic disease
  308. Mouth disease
  309. Multiple myeloma
  310. Multiple sclerosis
  311. Muscle tissue disease
  312. Muscular atrophy
  313. Muscular disease
  314. Musculoskeletal system disease
  315. Myasthenia gravis
  316. Myeloid leukemia
  317. Myeloma
  318. Myocardial infarction
  319. Myocardial ischemia
  320. Myocarditis
  321. Myopathy
  322. Myositis
  323. Nasal cavity disease
  324. Nephritis
  325. Nephropathia epidemica
  326. Nervous system cancer
  327. Nervous system disease
  328. Neurodegenerative disease
  329. Neuromuscular disease
  330. Neuromuscular junction disease
  331. Neuropathy
  332. Neutropenia
  333. Newborn respiratory distress syndrome
  334. non-Hodgkin lymphoma
  335. non-small cell lung carcinoma
  336. Normocytic anemia
  337. Nose disease
  338. Nutrition disease
  339. Obstructive jaundice
  340. Obstructive lung disease
  341. Opportunistic mycosis
  342. Organ system cancer
  343. Osteoarthritis
  344. Osteomyelitis
  345. Osteoporosis
  346. Osteosclerotic myeloma
  347. Otitis media
  348. Ovarian cancer
  349. Overnutrition
  350. Pancreas disease
  351. Pancreatic cancer
  352. Pancreatitis
  353. Pancytopenia
  354. Paranasal sinus disease
  355. Paraproteinemia
  356. Parasitic helminthiasis infectious disea
  357. Parasitic infectious disease
  358. Parasitic protozoa infectious disease
  359. Parkinson's disease
  360. Perinatal necrotizing enterocolitis
  361. Periodontal disease
  362. Periodontitis
  363. Peripheral nervous system disease
  364. Peripheral vascular disease
  365. Peritonitis
  366. Periventricular leukomalacia
  367. Pertussis
  368. Plasma cell neoplasm
  369. Plasma protein metabolism disease
  370. Plasmacytoma
  371. Plasmodium falciparum malaria
  372. Pleural disease
  373. Pleurisy
  374. Pneumoconiosis
  375. Pneumonia
  376. POEMS syndrome
  377. Polyarteritis nodosa
  378. Polyclonal hypergammaglobulinemia
  379. Polycystic ovary syndrome
  380. Polymyalgia rheumatica
  381. Polyneuropathy
  382. Polyradiculoneuropathy
  383. Polyradiculopathy
  384. pre-eclampsia
  385. Pregnancy complication
  386. Pregnancy disease
  387. Primary bacterial infectious disease
  388. Primary biliary cirrhosis
  389. Primary immunodeficiency disease
  390. Proliferative diabetic retinopathy
  391. Proliferative vitreoretinopathy
  392. Prostate cancer
  393. Prostate disease
  394. Prostatitis
  395. Proteinuria
  396. Psoriasis
  397. Psoriatic arthritis
  398. Psychotic disease
  399. Pulmonary edema
  400. Pulmonary fibrosis
  401. Pulmonary hypertension
  402. Pulmonary tuberculosis
  403. Pyelitis
  404. Pyelonephritis
  405. Radiculopathy
  406. Renal carcinoma
  407. Renal cell carcinoma
  408. Reproductive organ cancer
  409. Reproductive system disease
  410. Respiratory failure
  411. Respiratory system cancer
  412. Respiratory system disease
  413. Retinal degeneration
  414. Retinal detachment
  415. Retinal disease
  416. Retinal edema
  417. Retinal vascular disease
  418. Retinal vascular occlusion
  419. Retinal vein occlusion
  420. Rheumatic disease
  421. Rheumatoid arthritis
  422. Rhinitis
  423. Sarcoidosis
  424. Sarcoma
  425. Schizophrenia
  426. Scleroderma
  427. Sensory system disease
  428. Septic arthritis
  429. Severe acute respiratory syndrome
  430. Severe combined immunodeficiency
  431. Severe pre-eclampsia
  432. Sinusitis
  433. Skin disease
  434. Sleeping sickness
  435. Soft tissue cancer
  436. Spontaneous abortion
  437. Squamous cell carcinoma
  438. Stomach disease
  439. Sudden infant death syndrome
  440. Syndrome
  441. Synovitis
  442. Systemic lupus erythematosus
  443. Systemic mycosis
  444. Systemic scleroderma
  445. T-cell leukemia
  446. Taeniasis
  447. Tauopathy
  448. Temporal arteritis
  449. Tetanus
  450. Thoracic cancer
  451. Thrombocytopenia
  452. Thrombocytosis
  453. Thrombophilia
  454. Thyroid gland disease
  455. Thyroiditis
  456. Thyrotoxicosis
  457. Tooth disease
  458. Toxic encephalopathy
  459. Toxic shock syndrome
  460. Trypanosomiasis
  461. Tuberculosis
  462. Tularemia
  463. Typhoid fever
  464. Ulcerative colitis
  465. Upper respiratory tract disease
  466. Uremia
  467. Urinary bladder cancer
  468. Urinary system disease
  469. Urinary tract cancer
  470. Urinary tract disease
  471. Urticaria
  472. Uterine disease
  473. Uveal disease
  474. Uveitis
  475. Vaginal disease
  476. Vaginitis
  477. Vascular disease
  478. Vascular skin disease
  479. Vasculitis
  480. Viral encephalitis
  481. Viral hepatitis
  482. Viral infectious disease
  483. Viral meningitis
  484. Vitreous disease

Stage Associations

This gene is associated with the following stages: